{"ok":true,"entry":{"slug":"losartan","kind":"medication","name":"losartan","aliases":["Cozaar","losartan potassium"],"brands_sg":["Cozaar","Angizaar","Lozarsin","Rosart","Myotan"],"class":"angiotensin II receptor blocker","tags":["heart-bp"],"use_for":"prescribed for high blood pressure and heart failure","use_after":"nhs: usually once a day, at the same time every day","use_duration":null,"take_with":"water · nhs: with or without food, but no grapefruit juice","pros":["nhs: usually once a day, with or without food","healthhub: blocks angiotensin ii at blood vessel walls","nhs: may also suit children aged 6 to 17"],"cons":["nhs: dizziness, tiredness, headache, oedema","healthhub: potassium and kidney function get monitored","healthhub: can injure a developing fetus in pregnancy"],"dose_note":"the us fda label for cozaar states 'The usual starting dose of COZAAR is 50 mg once daily. The dosage can be increased to a maximum dose of 100 mg once daily as needed to control blood pressure' — 100 mg once daily is the adult label maximum; the same label starts at 25 mg once daily in possible intravascular depletion and in mild-to-moderate hepatic impairment. sg-registered single-ingredient tablets are 50 mg and 100 mg. in singapore the prescriber sets the dose.","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["pregnancy — healthhub: can injure and kill a developing fetus","severe heart failure, or liver problems (nhs)","past angioedema, or a reaction to another arb (nhs)","vomiting, diarrhoea or fever — nhs: dehydration risk"],"clashes":[{"src":["nhs_losa_mix"],"note":"nhs lists supplements and salt substitutes that contain potassium among those that may not mix well","with":"potassium supplements and salt substitutes"},{"src":["nhs_losa_mix"],"note":"nhs lists non-steroidal anti-inflammatory drugs among medicines that may not mix well with losartan","with":"nsaids including ibuprofen"},{"src":["nhs_losa_mix"],"note":"nhs lists beta blockers, ace inhibitors such as lisinopril, and diuretics such as spironolactone","with":"other blood pressure medicines and diuretics"},{"src":["nhs_losa_mix"],"note":"nhs lists lithium among medicines that may not mix well with losartan","with":"lithium"},{"src":["nhs_losa_food"],"food":true,"note":"nhs: it can stop the medicine working properly","with":"grapefruit juice"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, pulled in full via datastore_search and filtered locally)","quote":"All 35 registered losartan products (19 single-ingredient) carry Forensicclassification 'Prescription Only' — SIN08588P COZAAR TABLET 50 mg · SIN13720P Angizaar-50mg · SIN15076P LOZARSIN · SIN14314P ROSART · SIN14475P MYOTAN","accessed":"2026-08-27"},{"id":"nhs_losa_about","url":"https://www.nhs.uk/medicines/losartan/","label":"NHS Medicines A-Z — Losartan: what losartan is for","quote":"Losartan is a medicine used to treat high blood pressure and heart failure. It's only available on prescription … a type of medicine called an angiotensin receptor blocker (ARB).","accessed":"2026-08-27"},{"id":"nhs_losa_howto","url":"https://www.nhs.uk/medicines/losartan/","label":"NHS Medicines A-Z — Losartan: how to take losartan","quote":"Most people need to take losartan once a day … take it at any time of day, but try to take it at the same time every day; take it with water, with or without food","accessed":"2026-08-27"},{"id":"nhs_losa_side","url":"https://www.nhs.uk/medicines/losartan/","label":"NHS Medicines A-Z — Losartan: side effects","quote":"Common side effects of losartan can include: dizziness; tiredness; headache; tummy pain; feeling sick (nausea) or being sick (vomiting); swelling in your legs, ankles or feet (oedema)","accessed":"2026-08-27"},{"id":"nhs_losa_who","url":"https://www.nhs.uk/medicines/losartan/","label":"NHS Medicines A-Z — Losartan: who can and cannot take it","quote":"Most adults aged 18 years or over can take losartan. Losartan may also be suitable for children aged 6 to 17 years old … not suitable if: … severe heart failure … problems with your liver … angioedema","accessed":"2026-08-27"},{"id":"nhs_losa_mix","url":"https://www.nhs.uk/medicines/losartan/","label":"NHS Medicines A-Z — Losartan: taking it with other medicines","quote":"other medicines used to treat high blood pressure, including beta blockers and ACE inhibitors like lisinopril; … diuretics, such as spironolactone; supplements and salt substitutes … that contain potassium; some NSAIDs … lithium","accessed":"2026-08-27"},{"id":"nhs_losa_food","url":"https://www.nhs.uk/medicines/losartan/","label":"NHS Medicines A-Z — Losartan: food, drink and alcohol","quote":"avoid drinking grapefruit juice because it can stop your medicine working properly. Try to limit the amount of alcohol you drink while taking losartan because it can increase the risk of side effects.","accessed":"2026-08-27"},{"id":"hh_losa_uses","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/losartan","label":"HealthHub (Pharmaceutical Society of Singapore) — Losartan: what is this medication for","quote":"Losartan lowers blood pressure by blocking the effects of a substance called Angiotensin II at the blood vessel walls. This medication can also be used for patients who have protein in their urine","accessed":"2026-08-27"},{"id":"hh_losa_precautions","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/losartan","label":"HealthHub — Losartan: precautions","quote":"Inform your doctor if you are pregnant or planning to get pregnant … Taking this medication can cause injury and death to your developing fetus. Your doctor may need to monitor your potassium levels and kidney function","accessed":"2026-08-27"},{"id":"fda_cozaar_dose","url":"https://api.fda.gov/drug/label.json?search=openfda.brand_name:%22COZAAR%22&limit=1","label":"US FDA label for COZAAR (losartan potassium), section 2 Dosage and Administration, via openFDA drug/label.json (effective 2026-01-20)","quote":"The usual starting dose of COZAAR is 50 mg once daily. The dosage can be increased to a maximum dose of 100 mg once daily as needed to control blood pressure … A starting dose of 25 mg is recommended","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:24.715168+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}