{"ok":true,"entry":{"slug":"loratadine","kind":"medication","name":"loratadine","aliases":[],"brands_sg":["Clarityne"],"class":"antihistamine (non-drowsy)","tags":["allergy"],"use_for":"allergy symptoms — runny nose, sneezing, itchy eyes/skin","use_after":"label: once a day as needed · max 1 tablet in 24 h","use_duration":null,"take_with":"water · with or without food","pros":["non-drowsy — less sleepy than older antihistamines","once-a-day dosing","clarityne is general sale list in sg"],"cons":["can still make some people slightly sleepy","10 of 14 sg loratadine products are pharmacy-only","can blunt allergy skin tests (smpc: stop 48 h before)"],"dose_note":"sg clarityne label: adults and children 6+ (>30 kg) 1 tablet (10 mg) daily, not more than 1 tablet in 24 h; nhs: usual adult dose 10 mg once a day, usually lower with liver problems; us label: taking more than directed may cause drowsiness — as directed on the label or by your pharmacist","dosage":null,"ul_status":null,"sg_class":"pharmacy-only","cautions":["liver or kidney problems — ask a doctor; the dose may differ","pregnant or breastfeeding — check with a healthcare professional","epilepsy or seizure risk — tell your pharmacist first","heart rhythm problems — inform your healthcare professional"],"clashes":[{"src":["emc_clarityn_smpc","nhs_loratadine_interactions"],"note":"smpc: raise loratadine levels, no clinically significant changes seen in trials; nhs: tell your doctor","with":"cyp3a4 / cyp2d6 inhibitors (ketoconazole, erythromycin, cimetidine)"},{"src":["nhs_loratadine_interactions"],"note":"nhs: tell your doctor if you're taking it","with":"amiodarone"},{"src":["healthhub_loratadine"],"note":"healthhub: check before taking two otc products together to prevent overdosing","with":"other antihistamines, incl. cold & flu combination products"},{"src":["nhs_loratadine_interactions"],"note":"nhs: loratadine might make these side effects worse","with":"sedating medicines (sleepy, dry mouth, hard to pee)"}],"sources":[{"id":"healthhub_loratadine","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/loratadine","label":"HealthHub (MOH Singapore) — Loratadine, article last reviewed 03 June 2026","quote":"Loratadine belongs to a group of medicines known as antihistamines. It can be used for the relief of: Runny nose (due to a cold, flu or allergies), Itch in the eyes, nose or skin (due to an insect bite or allergies), Redness and swelling of the skin and eyes … Take the medication when necessary to relieve your symptoms … You may take this medication with or without food … Inform your healthcare professional if … You are pregnant, planning to become pregnant, or breastfeeding … You have: Liver or kidney problems, Heart or abnormal heart rhythm problems … Loratadine is a newer antihistamine that is less likely to cause drowsiness … Many over-the-counter medications contain antihistamines, always check with your healthcare professional before taking two over-the-counter medications at the same time to prevent overdosing","accessed":"2026-08-27"},{"id":"clarityne_sg_label","url":"https://www.clarityne.com.sg/products/clarityne/tablets-24hr","label":"Clarityne Singapore — Clarityne® Tablets 24-Hour product page (Bayer), directions","quote":"Temporarily relieves … runny itchy nose, itchy watery eyes, sneezing, and itchy skin rash … Non-drowsy multiple allergy symptoms relief … Adults and children 6 years and over (>30kg): 1 tablet daily; not more than 1 tablet in 24 hours … Consumers with liver or kidney disease: Ask a doctor","accessed":"2026-08-27"},{"id":"nhs_loratadine_about","url":"https://www.nhs.uk/medicines/loratadine/about-loratadine/","label":"NHS medicines A–Z — About loratadine","quote":"Loratadine is an antihistamine medicine that helps to relieve the symptoms of allergies. It can be used for: hay fever, conjunctivitis (red, itchy eyes), eczema, hives (urticaria), reactions to insect bites and stings, some food allergies. Loratadine is a non-drowsy antihistamine. It's much less likely to make you feel sleepy than some other antihistamines … You'll usually take loratadine once a day … Loratadine is classed as a non-drowsy antihistamine, but some people still find it makes them feel slightly sleepy","accessed":"2026-08-27"},{"id":"nhs_loratadine_dose","url":"https://www.nhs.uk/medicines/loratadine/how-and-when-to-take-loratadine/","label":"NHS medicines A–Z — How and when to take loratadine","quote":"The usual dose in adults is 10mg, taken once a day. Doses are usually lower for people with liver problems and may be taken every other day … You can take all types of loratadine with or without food","accessed":"2026-08-27"},{"id":"nhs_loratadine_who","url":"https://www.nhs.uk/medicines/loratadine/who-can-and-cannot-take-loratadine/","label":"NHS medicines A–Z — Who can and cannot take loratadine","quote":"tell your doctor or pharmacist before taking it if you: have ever had an allergy to loratadine or any other medicines, have severe liver failure, have an allergy to food additives, have epilepsy or another condition that puts you at risk of seizures or fits, are due to have a test for allergies – taking loratadine may affect the results","accessed":"2026-08-27"},{"id":"nhs_loratadine_interactions","url":"https://www.nhs.uk/medicines/loratadine/taking-loratadine-with-other-medicines-and-herbal-supplements/","label":"NHS medicines A–Z — Taking loratadine with other medicines and herbal supplements","quote":"Some medicines affect how loratadine works or can increase the chances of you having side effects. Tell your doctor if you're taking: amiodarone, a medicine used to treat an irregular heartbeat; cimetidine, an indigestion medicine; erythromycin, an antibiotic; any medicine that makes you feel sleepy, gives you a dry mouth or makes it difficult for you to pee – taking loratadine might make these side effects worse","accessed":"2026-08-27"},{"id":"nhs_loratadine_side_effects","url":"https://www.nhs.uk/medicines/loratadine/side-effects-of-loratadine/","label":"NHS medicines A–Z — Side effects of loratadine","quote":"The most common side effect of loratadine is feeling sleepy. This happens in more than 1 in 100 people","accessed":"2026-08-27"},{"id":"dailymed_claritin","url":"https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=660ac9df-f1b1-4c89-94dd-9fae0a013f3c","label":"FDA DailyMed — Claritin (loratadine 10 mg) tablets Drug Facts label, Bayer HealthCare LLC, setid 660ac9df-f1b1-4c89-94dd-9fae0a013f3c","quote":"temporarily relieves these symptoms due to hay fever or other upper respiratory allergies: runny nose, itchy, watery eyes, sneezing, itching of the nose or throat … Ask a doctor before use if you have liver or kidney disease. Your doctor should determine if you need a different dose … do not take more than directed. Taking more than directed may cause drowsiness … If pregnant or breast-feeding, ask a health professional before use … adults and children 6 years and over: 1 tablet daily; not more than 1 tablet in 24 hours","accessed":"2026-08-27"},{"id":"emc_clarityn_smpc","url":"https://www.medicines.org.uk/emc/product/3506/smpc","label":"UK emc — Clarityn Allergy 10mg Tablets (GSL) Summary of Product Characteristics, Bayer (sections 4.2, 4.4, 4.5, 4.6, 5.2)","quote":"One tablet once daily … should be administered with caution in patients with severe liver impairment … should be discontinued at least 48 hours before skin tests since antihistamines may prevent or reduce otherwise positive reactions … Potential interaction may occur with all known inhibitors of CYP3A4 or CYP2D6 resulting in elevated levels of loratadine … Increase in plasma concentrations of loratadine has been reported after concomitant use with ketoconazole, erythromycin, and cimetidine in controlled trials, but without clinically significant changes (including electrocardiographic) … As a precautionary measure, it is preferable to avoid the use of Clarityn Allergy Tablets during pregnancy … Concomitant ingestion of food can delay slightly the absorption of loratadine but without influencing the clinical effect","accessed":"2026-08-27"},{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg dataset d_767279312753558cbf19d48344577084, managed by Health Sciences Authority, last updated 7 Aug 2026), Forensicclassification column","quote":"CLARITYNE TABLET 10mg | SIN14077P | General Sale List; CLARITYNE SYRUP 5 MG/5 ML (GRAPE FLAVOR) | SIN16091P | General Sale List — single-ingredient oral loratadine: 4 General Sale List / 10 Pharmacy Only of 14 rows (e.g. ALLORIS, LORFAST, LORIDIN RAPITAB, SUNADINE 10 mg, LORADINE TABLET 10 mg [SIN13341P, ingredient listed as 'Loratadine (micronized)'] = Pharmacy Only; CARIN 10 mg, LORADINE syrup = GSL) (pulled via datastore_search API, re-counted by verifier 27 Aug 2026)","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:24.715168+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}