{"ok":true,"entry":{"slug":"loperamide","kind":"medication","name":"loperamide","aliases":["Imodium","Lomide"],"brands_sg":["Imodium","Eldoper","Colodium","Loramide","Vacontil"],"class":"antidiarrhoeal","tags":["digestive"],"use_for":"short-term diarrhoea · ibs diarrhoea diagnosed by a doctor","use_after":"label: no more than 8 capsules in any 24 hour period","use_duration":null,"take_with":"liquid · with or without food","pros":["nhs: usually eases diarrhoea within about 1 hour","sold in sg pharmacies without a prescription","sg label: makes stools more solid and less frequent"],"cons":["over the label max can cause serious heart problems","not for bloody stools, fever or antibiotic diarrhoea","nhs: not past 48 h without talking to a doctor"],"dose_note":"sg imodium 2 mg capsule label (national drug formulary): “do not take more than 8 capsules in any 24 hour period”; nhs puts the maximum at 6 capsules or tablets in 24 hours if bought from a shop or pharmacy and 8 on prescription, and says not to take it for more than 48 hours without talking to a doctor — as directed on the label or by your pharmacist","dosage":null,"ul_status":null,"sg_class":"pharmacy-only","cautions":["blood in the stools or a high temperature — sg label: do not use","flare-up of an inflammatory bowel condition, or severe diarrhoea after antibiotics — nhs: do not take","liver problems — nhs: talk to your doctor first","heart conditions, incl. irregular heart rhythm, or liver disease — healthhub: inform your healthcare professional"],"clashes":[{"src":["nhs_lop_interactions"],"note":"nhs: tell your doctor or pharmacist if you're taking them","with":"clozapine, ritonavir, quinidine"},{"src":["nhs_lop_interactions"],"note":"nhs: tell your doctor or pharmacist if you're taking them","with":"other medicines for diarrhoea or constipation"},{"src":["nhs_lop_interactions"],"note":"nhs: speak to your doctor if your diarrhoea is very severe","with":"metformin, blood pressure or heart failure medicines"}],"sources":[{"id":"nhs_lop_about","url":"https://www.nhs.uk/medicines/loperamide/about-loperamide/","label":"NHS medicines A–Z — About loperamide (brand name: Imodium), page last reviewed 10 April 2024","quote":"Loperamide is a medicine to treat diarrhoea (runny poo). It can help with short-term diarrhoea or irritable bowel syndrome (IBS) … Loperamide works by slowing down food as it goes through your gut","accessed":"2026-08-27"},{"id":"nhs_lop_keyfacts","url":"https://www.nhs.uk/medicines/loperamide/about-loperamide/","label":"NHS medicines A–Z — About loperamide, Key facts","quote":"Loperamide usually starts to make your diarrhoea better within 1 hour. If you buy loperamide … do not take it for more than 48 hours without talking to a doctor … Too much loperamide can cause serious heart problems","accessed":"2026-08-27"},{"id":"nhs_lop_dose","url":"https://www.nhs.uk/medicines/loperamide/how-and-when-to-take-loperamide/","label":"NHS medicines A–Z — How and when to take loperamide","quote":"The recommended maximum dose in 24 hours is: 6 capsules or tablets, if you buy loperamide from a shop or a pharmacy; 8 … if you have a prescription … You can take loperamide with or without food","accessed":"2026-08-27"},{"id":"nhs_lop_who","url":"https://www.nhs.uk/medicines/loperamide/who-can-and-cannot-take-loperamide/","label":"NHS medicines A–Z — Who can and cannot take loperamide, Who can take loperamide","quote":"Loperamide is available to buy without a prescription for: anyone aged 12 years or over with short-term diarrhoea; adults … with short-term diarrhoea caused by irritable bowel syndrome (IBS), but only if a doctor has diagnosed IBS","accessed":"2026-08-27"},{"id":"nhs_lop_notfor","url":"https://www.nhs.uk/medicines/loperamide/who-can-and-cannot-take-loperamide/","label":"NHS medicines A–Z — Who can and cannot take loperamide, Who may not be able to take loperamide","quote":"Do not take loperamide if you: have severe diarrhoea after taking antibiotics; are having a flare-up of an inflammatory bowel condition … Talk to your doctor … if you have liver problems … blood in your poo and a high temperature","accessed":"2026-08-27"},{"id":"nhs_lop_interactions","url":"https://www.nhs.uk/medicines/loperamide/taking-loperamide-with-other-medicines-and-herbal-supplements/","label":"NHS medicines A–Z — Taking loperamide with other medicines and herbal supplements","quote":"Tell your doctor or pharmacist if you're taking: clozapine … ritonavir … quinidine … other medicines for diarrhoea, constipation … Speak to your doctor if your diarrhoea is very severe and you take metformin … or medicines for high blood pressure or heart failure","accessed":"2026-08-27"},{"id":"healthhub_loperamide","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/loperamide","label":"HealthHub (MOH Singapore) — Loperamide, medication information leaflet, article last reviewed 01 July 2026","quote":"Loperamide is used to treat diarrhoea. It works by slowing down the movement of stools in your bowels … Inform your healthcare professional if … You have any heart conditions, including those associated with irregular heart rhythm or liver disease","accessed":"2026-08-27"},{"id":"ndf_imodium","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin06212p/","label":"Singapore National Drug Formulary — IMODIUM CAPSULE 2 MG [SIN06212P] product information (indication, dosing, forensic classification), last updated 28 July 2026","quote":"IMODIUM® is used to treat diarrhea. IMODIUM® makes the stools more solid and less frequent … The capsules should be taken with liquid … But: Do not take more than 8 capsules in any 24 hour period! … Forensic Classification PHARMACY ONLY MEDICINES","accessed":"2026-08-27"},{"id":"ndf_imodium_ci","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin06212p/","label":"Singapore National Drug Formulary — IMODIUM CAPSULE 2 MG [SIN06212P], Contraindications","quote":"Do not give IMODIUM® 2MG CAPSULE to children under 2 years. Do not use IMODIUM® 2MG CAPSULE: If there is blood in your stools or you have a high temperature; If you have inflammation of the lower bowel","accessed":"2026-08-27"},{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg dataset d_767279312753558cbf19d48344577084, managed by Health Sciences Authority, last updated 7 Aug 2026), Forensicclassification column","quote":"IMODIUM CAPSULE 2 mg | SIN06212P | Pharmacy Only — all 7 single-ingredient oral loperamide products in the register are Pharmacy Only (ELDOPER, COLODIUM, LORAMIDE, VACONTIL, ABYDIUM capsules; LORPA SYRUP 1mg/5ml) (pulled via datastore_search API, 27 Aug 2026)","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:24.715168+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}