{"ok":true,"entry":{"slug":"lavender","kind":"supplement","name":"lavender","aliases":["Lavandula angustifolia","Silexan"],"brands_sg":["NOW Foods","Cococare","artnaturals","Vitacost","Aura Cacia"],"class":"botanical","tags":["sleep"],"use_for":"anxiety symptoms; the sleep evidence is unclear","use_after":"trials dosed 80 mg once daily","use_duration":"the trials ran 10 weeks","take_with":null,"pros":["80 mg/day silexan beat placebo for anxiety","trial side effects were burping and mild gi upset","no dependence or withdrawal seen in trials"],"cons":["benefit for sleep or insomnia stays unclear","trials small, not independently funded","oral capsule data does not carry over to oils"],"dose_note":"trials used 80 mg a day of silexan, a lavender oil preparation, for 10 weeks; that is the anxiety literature, not a sleep dose","dosage":{"ul":null,"unit":"mg","fda_dv":null,"rda_ai":null,"ul_status":"none_established","population":"general adult","hsa_max_daily":null},"ul_status":"none_established","sg_class":null,"cautions":["pregnancy or breastfeeding — little is known about safety","before surgery, or alongside sedatives — a theoretical interaction","topical lavender can cause allergic skin reactions","not listed in hsa's annexes — that is not a safety clearance"],"clashes":[{"src":["nccih_lavender_safety"],"note":"theoretical interaction; nccih flags it ahead of surgery","with":"sedative drugs or herbs"}],"sources":[{"id":"nccih_lavender","url":"https://www.nccih.nih.gov/health/lavender","label":"NIH NCCIH — Lavender","quote":"It's unclear whether aromatherapy with lavender oil has benefits for anxiety, stress, symptoms of depression, some types of pain, sleep quality or insomnia … the research has several limitations, such as the small sample sizes","accessed":"2026-08-27"},{"id":"nccih_lavender_safety","url":"https://www.nccih.nih.gov/health/lavender","label":"NIH NCCIH — Lavender, \"What Do We Know About Safety?\"","quote":"There are theoretical reasons to suspect that lavender might interact with some sedative drugs or herbs … Topical products containing lavender may cause allergic skin reactions in some people.","accessed":"2026-08-27"},{"id":"kasper2025","url":"https://europepmc.org/article/MED/39453446","label":"Silexan in anxiety, depression, and related disorders (Kasper et al., Eur Arch Psychiatry Clin Neurosci 2025)","quote":"Silexan taken orally at a daily dose of 80 mg for 10 weeks was significantly superior to placebo in reducing psychic and somatic symptoms of anxiety and was as effective as 0.5 mg/d lorazepam","accessed":"2026-08-27"},{"id":"kasper2025_safety","url":"https://europepmc.org/article/MED/39453446","label":"Silexan in anxiety, depression, and related disorders — tolerability (Kasper et al. 2025)","quote":"Adverse events associated with silexan in clinical trials were limited to eructation and mild, transient gastrointestinal complaints. The herbal product was not associated with drug interactions, sedation, sleep disturbance, dependence and abuse potential","accessed":"2026-08-27"},{"id":"hsa_pr","url":"https://file.go.gov.sg/hsa-chp-prohibited-restricted-ing-guidelines.pdf","label":"HSA — Guidelines on Prohibited and Restricted Ingredients in Health Supplements and Traditional Medicines (Oct 2025, GL-CHPB-1-012)","quote":"The objective of this guideline is to highlight the substances of concern when used in HS and TM and is not meant to be an exhaustive list.","accessed":"2026-08-27"},{"id":"hsa_hs","url":"https://file.go.gov.sg/hsa-hs-guidelines.pdf","label":"HSA — Health Supplements Guidelines (Jan 2026, GL-CHPB-3-001 Rev. 020), Tables 4–5","quote":"HS for use by the general adult population should not contain vitamins and minerals exceeding the stipulated limits stated in Tables 4 and 5.","accessed":"2026-08-27"},{"id":"iherb_sg","url":"https://sg.iherb.com/c/lavender-oil","label":"iHerb Singapore — category listing (default order)","quote":"Lavender Essential Oil: Pure Calming Diffuser Oil | iHerb","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:23.779398+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}