{"ok":true,"entry":{"slug":"lactobacillus-acidophilus","kind":"supplement","name":"lactobacillus acidophilus","aliases":["L. acidophilus","acidophilus"],"brands_sg":["California Gold Nutrition","21st Century","Garden of Life","NOW Foods","Lemme"],"class":"probiotic","tags":["gut"],"use_for":"bloating and ibs pain — small, strain-specific trials","use_after":null,"use_duration":"symptom scores moved over 6–8 weeks in these trials","take_with":"capsules twice a day in the bloating trial","pros":["bloating improved vs placebo at 4 and 8 weeks","dds-1 beat placebo on ibs pain scores (n=330)","stool consistency normalised vs placebo in ibs"],"cons":["limited human evidence for the species on its own","most trials pair it with other strains","the bloating trial was small — 60 patients"],"dose_note":"the bloating trial used 2×10^11 cfu a day of ncfm with bi-07; the ibs trial used 1×10^10 cfu a day of dds-1","dosage":{"ul":null,"unit":"CFU","fda_dv":null,"rda_ai":null,"ul_status":"none_established","population":"general adult","hsa_max_daily":null},"ul_status":"none_established","sg_class":null,"cautions":["severe illness or weakened immunity — higher risk of harm","premature infants — fda warned of severe or fatal infections"],"clashes":[],"sources":[{"id":"nccih_probiotics","url":"https://www.nccih.nih.gov/health/probiotics-what-you-need-to-know","label":"NIH NCCIH — Probiotics: Usefulness and Safety","quote":"Different types of probiotics may have different effects. For example, if a specific kind of Lactobacillus helps prevent an illness, that doesn't necessarily mean that another kind of Lactobacillus … would do the same thing.","accessed":"2026-08-27"},{"id":"nccih_safety","url":"https://www.nccih.nih.gov/health/probiotics-what-you-need-to-know","label":"NIH NCCIH — Probiotics: Usefulness and Safety, \"Can probiotics be harmful?\"","quote":"The risk of harmful effects from probiotics is greater in people with severe illnesses or compromised immune systems … Cases of severe or fatal infections have been reported in premature infants who were given probiotics","accessed":"2026-08-27"},{"id":"ringel2011","url":"https://europepmc.org/article/MED/21436726","label":"Probiotic bacteria Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 versus placebo for the symptoms of bloating in functional bowel disorders (Ringel-Kulka et al., J Clin Gastroenterol 2011)","quote":"a double-blind, placebo-control clinical trial of the probiotic bacterias L-NCFM and B-LBi07 twice a day (2×10(11) CFU/d) versus placebo over 8 weeks … Sixty patients … Abdominal bloating improved in the probiotics compared with the placebo group","accessed":"2026-08-27"},{"id":"martoni2020","url":"https://europepmc.org/article/MED/32019158","label":"Lactobacillus acidophilus DDS-1 and Bifidobacterium lactis UABla-12 improve abdominal pain severity and symptomology in IBS (Martoni et al., Nutrients 2020)","quote":"Three hundred and thirty adults … with IBS … L. acidophilus DDS-1 (1 × 10^10 CFU/day) … APS-NRS was significantly improved in both probiotic groups vs. placebo … normalization … in stool consistency in both probiotic groups","accessed":"2026-08-27"},{"id":"iherb_sg","url":"https://sg.iherb.com/c/probiotics","label":"iHerb Singapore — Probiotics category page (default best-selling order)","quote":"California Gold Nutrition, LactoBif® 30 Probiotics, 60 Veggie Capsules","accessed":"2026-08-27"},{"id":"hsa_pr","url":"https://file.go.gov.sg/hsa-chp-prohibited-restricted-ing-guidelines.pdf","label":"HSA — Guidelines on prohibited and restricted ingredients in HS and TM (Oct 2025), Annex A/B","quote":"The objective of this guideline is to highlight the substances of concern when used in HS and TM and is not meant to be an exhaustive list.","accessed":"2026-08-27"},{"id":"hsa_hs","url":"https://file.go.gov.sg/hsa-hs-guidelines.pdf","label":"HSA — Health Supplements Guidelines (Jan 2026), working definition and Tables 4–5","quote":"Vitamins, minerals, amino acids, fatty acids, enzymes, probiotics and other bioactive substances … Table 4: Vitamins Limits … Table 5: Minerals Limits","accessed":"2026-08-27"}],"brand_certs":[{"brand":"Garden of Life","example":null,"programme":"NSF Certified for Sport","matching_products":0,"brand_total_certified":23},{"brand":"Lemme","example":null,"programme":"NSF Certified for Sport","matching_products":0,"brand_total_certified":1}],"updated_at":"2026-08-30T17:59:36.026222+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}