{"ok":true,"entry":{"slug":"insulin-lispro","kind":"medication","name":"insulin lispro","aliases":["Humalog"],"brands_sg":["Humalog KwikPen","Humalog Mix25 KwikPen","Humalog Mix50 KwikPen","Humalog Mix 25"],"class":"rapid-acting insulin","tags":["diabetes"],"use_for":"prescribed to control blood sugar levels after each meal","use_after":"healthhub: immediately or 15 minutes before a meal","use_duration":null,"take_with":"food · healthhub: alcohol raises low-blood-sugar risk","pros":["healthhub: rapid-acting, works with each meal","healthhub: can be injected just after a meal if needed","fda label: the pens dial in 1 unit steps"],"cons":["healthhub: low blood sugar is the main side effect","healthhub: injection-site lumps, dents or bruising","healthhub: discarded 4 weeks after first use"],"dose_note":"the us fda label for humalog states 'The dosage of HUMALOG must be individualized based on the route of administration and the individual's metabolic needs, blood glucose monitoring results and glycemic control goal' — it sets no maximum daily dose. the only maximum the label states is a device limit: 'The HUMALOG U-100 KwikPen, HUMALOG U-100 Tempo Pen and HUMALOG U-200 KwikPen each dial in 1 unit increments and delivers a maximum dose of 60 units per injection', and 'The HUMALOG U-100 Junior KwikPen dials in 0.5 unit increments and delivers a maximum dose of 30 units per injection'. only 100 units/ml humalog presentations are registered in singapore. in singapore the prescriber sets the dose.","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["an allergy to insulin lispro or any ingredient in it (healthhub)","drinking alcohol often (healthhub)","eating less than usual through illness or a diet change (healthhub)","pregnancy or breastfeeding, and travel across time zones (healthhub)"],"clashes":[{"src":["hh_lis_avoid","hh_lis_side"],"food":true,"note":"healthhub: it may increase the risk of low blood sugar, especially on an empty stomach","with":"alcohol"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached in full and filtered locally)","quote":"All 4 registered insulin lispro products carry Forensicclassification 'Prescription Only' — SIN13719P HUMALOG KWIKPEN 100 units/ml · SIN11171P HUMALOG MIX25 KWIKPEN · SIN14025P Humalog Mix50 Kwikpen · SIN11227P HUMALOG MIX 25 SUSPENSION FOR INJECTION.","accessed":"2026-08-27"},{"id":"hh_lis_uses","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/insulin-lispro","label":"HealthHub (Singapore) — Insulin Lispro: what is this medication for","quote":"Insulin Lispro is a rapid (fast) acting insulin. It is used to control blood sugar levels after each meal.","accessed":"2026-08-27"},{"id":"hh_lis_howto","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/insulin-lispro","label":"HealthHub — Insulin Lispro: how should I take or use this medication","quote":"Insulin Lispro is given immediately or 15 minutes before a meal as an injection into the fatty tissue that is between the skin and muscle layer … If you need to, you can inject immediately after a meal instead.","accessed":"2026-08-27"},{"id":"hh_lis_side","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/insulin-lispro","label":"HealthHub — Insulin Lispro: common side effects and low blood sugar","quote":"This medication may cause low blood sugar (hypoglycemia). Symptoms of low blood sugar include: Weakness; Dizziness; Hunger; Sweating; Trembling; Blurred vision; Walking unsteadily; Fast heartbeat … Drink alcohol on an empty stomach while injecting insulin","accessed":"2026-08-27"},{"id":"hh_lis_site","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/insulin-lispro","label":"HealthHub — Insulin Lispro: injection-site reactions","quote":"Some patients may also experience mild pain, redness, bruising, swelling, a small lump or dent of the skin at the injection site … They also usually go away in a few days to a few weeks.","accessed":"2026-08-27"},{"id":"hh_lis_storage","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/insulin-lispro","label":"HealthHub — Insulin Lispro: how should I store this medication","quote":"Store all unopened insulin in a refrigerator between 2 to 8 degrees Celsius. Do not freeze … Once the insulin has been first used, do not refrigerate … Discard the insulin 4 weeks after opening.","accessed":"2026-08-27"},{"id":"hh_lis_precautions","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/insulin-lispro","label":"HealthHub — Insulin Lispro: what precautions should I take","quote":"Are allergic to this medication or any of the other ingredients of this medication; Drink alcohol often; Are eating less than usual due to sickness/a changed diet … Are travelling across different time zones … Are pregnant or breastfeeding","accessed":"2026-08-27"},{"id":"hh_lis_avoid","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/insulin-lispro","label":"HealthHub — Insulin Lispro: what food or medication should I avoid","quote":"Avoid taking alcohol with this medication as this may increase your risk of having low blood sugar.","accessed":"2026-08-27"},{"id":"fda_humalog_individual","url":"https://api.fda.gov/drug/label.json?search=openfda.brand_name:%22HUMALOG%22&limit=1","label":"US FDA label for HUMALOG (insulin lispro), section 2 Dosage and Administration, via openFDA (Eli Lilly, effective 2024-01-24)","quote":"The dosage of HUMALOG must be individualized based on the route of administration and the individual's metabolic needs, blood glucose monitoring results and glycemic control goal.","accessed":"2026-08-27"},{"id":"fda_humalog_pen","url":"https://api.fda.gov/drug/label.json?search=openfda.brand_name:%22HUMALOG%22&limit=1","label":"US FDA label for HUMALOG, section 2.3 Dosing Information (pen delivery limits), via openFDA","quote":"The HUMALOG U-100 KwikPen, HUMALOG U-100 Tempo Pen and HUMALOG U-200 KwikPen each dial in 1 unit increments and delivers a maximum dose of 60 units per injection. The HUMALOG U-100 Junior KwikPen dials in 0.5 unit increments","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:23.779398+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}