{"ok":true,"entry":{"slug":"ibuprofen","kind":"medication","name":"ibuprofen","aliases":[],"brands_sg":["Nurofen"],"class":"nsaid · analgesic","tags":["pain-fever"],"use_for":"pain and inflammation relief · brings down fever","use_after":"label: up to 3× a day as needed · at least 4 h between doses","use_duration":null,"take_with":"water · with meals or after food to limit stomach upset","pros":["also reduces inflammation, not just pain","200 mg packs are general sale list in sg (nurofen)","adults can take it alongside paracetamol (nhs)"],"cons":["stomach irritation and bleeding risk, more so at 60+","400 mg strength is prescription-only in sg","labels cap use at 10 days without a doctor"],"dose_note":"sg nurofen 200 mg label: 1–2 tablets with water up to three times a day as required, at least 4 h between doses, max 6 tablets (1,200 mg) in 24 h, short-term use only; us advil label: 1 tablet every 4–6 h, 2 if needed, not more than 6 in 24 h unless a doctor directs; nhs: smallest dose you need for the shortest time — as directed on the label or by your pharmacist","dosage":null,"ul_status":null,"sg_class":"pharmacy-only","cautions":["stomach ulcer or bleeding history — labels say do not take","asthma, kidney, heart or liver condition — ask a doctor first","pregnant or trying — sg label: avoid if possible; ask a doctor first","dengue symptoms (high fever, severe headache) — sg label: do not take"],"clashes":[{"src":["healthhub_ibuprofen","nhs_ibuprofen","nurofen_sg_label"],"note":"healthhub: avoid taking together; nhs: do not take at the same time","with":"other nsaids (aspirin, naproxen, diclofenac)"},{"src":["healthhub_ibuprofen","dailymed_advil","nhs_ibuprofen"],"note":"healthhub: can interact; us label: stomach-bleeding chance higher with anticoagulants, and ibuprofen may blunt heart-protective aspirin","with":"blood thinners (warfarin, clopidogrel, aspirin)"},{"src":["dailymed_ibuprofen_rx","nhs_ibuprofen"],"note":"us rx label: nsaids may diminish the antihypertensive effect of ace-inhibitors; nhs: may not mix well","with":"ace inhibitors and other blood-pressure medicines"},{"src":["dailymed_advil","dailymed_ibuprofen_rx"],"note":"us label: ask a doctor before use if taking a diuretic; rx label: impaired response to thiazide or loop diuretics","with":"diuretics (water tablets)"},{"src":["nhs_ibuprofen","dailymed_advil"],"note":"nhs: may not mix well; us label: steroid drugs raise the stomach-bleeding chance","with":"steroid medicines and antidepressants"}],"sources":[{"id":"healthhub_ibuprofen","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/ibuprofen-oral","label":"HealthHub (MOH Singapore) — Ibuprofen Oral, article last reviewed 07 July 2026","quote":"Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) which is commonly used to treat pain and reduce inflammation. It can also be used to bring down the body temperature during a fever and to relieve headaches, joint or muscle pain … Ibuprofen should be best taken with meals to reduce stomach irritation … It is available over the counter without a prescription for short-term relief of fever, mild to moderate pain and inflammation … Inform your healthcare professional if … You are pregnant, planning to become pregnant, or breastfeeding … You have a history of stomach or bowel ulcers or bleeding, or bleeding problems. You have asthma. You have a history of kidney, heart problems or stroke … Ibuprofen should be used at the lowest effective dose and for the shortest possible time … Ibuprofen can interact with blood-thinning medications (e.g. Aspirin, Clopidogrel, Warfarin). Ibuprofen is a NSAID, hence avoid taking together with other NSAIDs (e.g. Naproxen, Diclofenac). Avoid taking excessive amounts of alcohol when taking Ibuprofen as this will increase the risk of bleeding in the stomach","accessed":"2026-08-27"},{"id":"nurofen_sg_label","url":"https://www.nurofen.com.sg/our-products/core/nurofen-coated-tablets-200mg-ibuprofen/","label":"Nurofen Singapore — Nurofen Coated Tablets 200mg Ibuprofen, product page directions and safety information (Reckitt)","quote":"For oral administration and short-term use only. Adults and children over 12 years: Swallow 1 or 2 tablets with water, up to three times a day as required. Leave at least 4 hours between doses. Do not exceed 6 tablets in 24 hours … do not take if you: Experience symptoms of dengue fever (eg high fever, severe headache, muscle and joint pains); Have or have ever had a stomach ulcer, perforation or bleeding; Are allergic to ibuprofen, to any of the ingredients, or to aspirin or other painkillers; Are taking other NSAID pain killers (eg. Ibuprofen, naproxen or aspirin) with a daily dose above 75mg; Have severe kidney, liver or heart problems. The use of ibuprofen during pregnancy should if possible, be avoided … Nurofen can be taken without food when used at low dose and for short duration","accessed":"2026-08-27"},{"id":"nhs_ibuprofen","url":"https://www.nhs.uk/medicines/ibuprofen-for-adults/","label":"NHS medicines A–Z — Ibuprofen for adults","quote":"Ibuprofen is a painkiller that helps relieve pain and reduce swelling (inflammation) … For most 200mg tablets and capsules: swallow 1 or 2 tablets or capsules whole with water (ideally with or after food), take them up to 3 times a day if you're still in pain, wait at least 4 hours between each dose, do not take more than 6 tablets or capsules in 24 hours … Do not take ibuprofen tablets and capsules for more than 10 days unless advised to by a doctor … it may not be suitable if: you've had an allergic reaction to ibuprofen, aspirin or another non-steroidal anti-inflammatory drug (NSAID), you have a stomach ulcer or you've had them before, you have asthma or allergies … you have a heart, liver or kidney condition … you're pregnant or trying to get pregnant … Common side effects … indigestion and stomach aches, feeling sick (nausea) … medicines … that may not mix well with ibuprofen. These include some types of: anticoagulants (such as warfarin), steroid medicines, antidepressants, medicines to lower blood pressure … Do not take ibuprofen at the same time as other non-steroidal anti-inflammatory drugs (NSAIDs), such as naproxen or aspirin","accessed":"2026-08-27"},{"id":"nhs_paracetamol","url":"https://www.nhs.uk/medicines/paracetamol-for-adults/","label":"NHS medicines A–Z — Paracetamol for adults (taking paracetamol with ibuprofen)","quote":"Adults can take paracetamol at the same time as ibuprofen if needed. But it's a good idea to try them on their own first to see if they help your pain","accessed":"2026-08-27"},{"id":"dailymed_advil","url":"https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1a665e64-9f30-be37-4a83-38789f1f1e89","label":"FDA DailyMed — Advil (ibuprofen 200 mg) tablets/caplets Drug Facts label, Haleon US Holdings LLC, setid 1a665e64-9f30-be37-4a83-38789f1f1e89","quote":"temporarily relieves minor aches and pains … temporarily reduces fever … Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you: are age 60 or older, have had stomach ulcers or bleeding problems, take a blood thinning (anticoagulant) or steroid drug, take other drugs containing prescription or non-prescription NSAIDs … Ask a doctor before use if … you have high blood pressure, heart disease, liver cirrhosis, kidney disease, asthma, or had a stroke, you are taking a diuretic. Ask a doctor or pharmacist before use if you are … taking aspirin for heart attack or stroke, because ibuprofen may decrease this benefit of aspirin … When using this product take with food or milk if stomach upset occurs … It is especially important not to use ibuprofen at 20 weeks or later in pregnancy unless definitely directed to do so by a doctor … take 1 tablet every 4 to 6 hours while symptoms persist; if pain or fever does not respond to 1 tablet, 2 tablets may be used; do not exceed 6 tablets in 24 hours, unless directed by a doctor … pain gets worse or lasts more than 10 days","accessed":"2026-08-27"},{"id":"dailymed_ibuprofen_rx","url":"https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=17577b3b-e755-45d1-8b53-775d058578b2","label":"FDA DailyMed — Ibuprofen Tablets USP 400/600/800 mg (Rx only) prescribing information, Amneal Pharmaceuticals LLC, setid 17577b3b-e755-45d1-8b53-775d058578b2 — Drug Interactions","quote":"ACE-inhibitors: Reports suggest that NSAIDs may diminish the antihypertensive effect of ACE-inhibitors … Patients taking thiazides or loop diuretics may have impaired response to these therapies when taking NSAIDs … because bleeding has been reported when ibuprofen tablets and other NSAIDs have been administered to patients on coumarin-type anticoagulants, the physician should be cautious","accessed":"2026-08-27"},{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg dataset d_767279312753558cbf19d48344577084, managed by Health Sciences Authority, last updated 7 Aug 2026), Forensicclassification column","quote":"NUROFEN TABLET 200MG (OTC) | SIN09488P | General Sale List; NUROFEN EXPRESS LIQUID CAPSULE 200MG | SIN14562P | General Sale List; NUROFEN TABLET 400MG | SIN14587P | Prescription Only; NUROFEN EXPRESS LIQUID CAPSULE 400mg | SIN14561P | Prescription Only; IBUFEN TABLETS 200 mg | SIN05464P | Pharmacy Only — single-ingredient oral ibuprofen: 5 GSL / 3 Pharmacy Only / 12 Prescription Only of 20 rows; no product named ADVIL in the register (pulled via datastore_search API, 27 Aug 2026)","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:21.812539+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}