{"ok":true,"entry":{"slug":"hydroxyzine","kind":"medication","name":"hydroxyzine","aliases":["Atarax"],"brands_sg":["Phymorax","AA Pharma Hydroxyzine","Hydroxyzine Mevon"],"class":"sedating antihistamine","tags":["allergy"],"use_for":"prescribed for itch, skin allergy and anxiety symptoms","use_after":"healthhub: with or without food, per the medicine label","use_duration":null,"take_with":"water · healthhub: alcohol adds to the sleepiness","pros":["healthhub: eases itch from allergy or insect bites","fda label: also used as a pre-anaesthetic sedative","sg register: 10 mg and 25 mg strengths are listed"],"cons":["healthhub: drowsiness, dizziness and dry mouth","fda label: contraindicated if the qt interval is long","fda label: contraindicated in early pregnancy"],"dose_note":"the us label for hydroxyzine hydrochloride states 'adults, 50 to 100 mg q.i.d.' for anxiety and tension, 'adults, 25 mg t.i.d. or q.i.d.' for pruritus, and '50 to 100 mg for adults' as a pre-anaesthetic sedative — the anxiety line is the highest adult regimen printed on that label, and it adds that effectiveness beyond four months 'has not been assessed by systematic clinical studies'. sg-registered strengths are 10 mg and 25 mg. in singapore the prescriber sets the dose.","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["healthhub: kidney or liver disease","healthhub: abnormal heart rhythm or high blood pressure","healthhub: glaucoma, enlarged prostate or seizures","fda label: contraindicated in early pregnancy"],"clashes":[{"src":["hh_hyd_food"],"food":true,"note":"healthhub: it can cause excessive sleepiness","with":"alcohol"},{"src":["fda_hyd_prec"],"note":"fda label: the potentiating action of hydroxyzine must be considered, and depressant dosage reduced","with":"cns depressants (opioids, barbiturates)"},{"src":["fda_hyd_prec"],"note":"fda label: caution is recommended during concomitant use of drugs known to prolong the qt interval","with":"qt-prolonging drugs (quinidine, amiodarone, sotalol)"},{"src":["fda_hyd_contra"],"note":"fda label: contraindicated in patients with known hypersensitivity to either","with":"cetirizine or levocetirizine allergy"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached in full and filtered locally)","quote":"All 5 registered hydroxyzine products carry Forensicclassification 'Prescription Only' — SIN09981P PHYMORAX TABLET 10 mg · SIN04096P and SIN04142P AA PHARMA HYDROXYZINE CAPSULE 10 mg and 25 mg · SIN16328P/SIN16329P HYDROXYZINE MEVON FILM-COATED TABLETS 25 MG and 10 MG.","accessed":"2026-08-27"},{"id":"hh_hyd_uses","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/hydroxyzine","label":"HealthHub (Pharmaceutical Society of Singapore) — Hydroxyzine: what is this medication for","quote":"Hydroxyzine belongs to a group of medicines known as antihistamines … Relief of itch in the eyes, nose or skin (due to an insect bite or allergies) … may also be used to treat symptoms of anxiety","accessed":"2026-08-27"},{"id":"hh_hyd_admin","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/hydroxyzine","label":"HealthHub — Hydroxyzine: how should I take or use this medication","quote":"Hydroxyzine may be taken with or without food. Take your medication according to the instructions stated on the medication label. Do not stop taking or adjust the dose of this medication without checking with your doctor.","accessed":"2026-08-27"},{"id":"hh_hyd_prec","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/hydroxyzine","label":"HealthHub — Hydroxyzine: precautions","quote":"You have or have ever had: Kidney or liver disease; High blood pressure or abnormal heart rhythm; Respiratory disease; … difficulty in urination, enlarged prostate gland … seizures (fits) or increased eye pressure (glaucoma)","accessed":"2026-08-27"},{"id":"hh_hyd_side","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/hydroxyzine","label":"HealthHub — Hydroxyzine: common side effects","quote":"The mentioned side effects generally affect up to 10% of patients. Drowsiness or feeling tired … Dizziness … Dry mouth … Constipation … Headache","accessed":"2026-08-27"},{"id":"hh_hyd_food","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/hydroxyzine","label":"HealthHub — Hydroxyzine: what food or medication should I avoid","quote":"Avoid drinking alcohol while taking Hydroxyzine as it can cause excessive sleepiness.","accessed":"2026-08-27"},{"id":"fda_hyd_dose","url":"https://api.fda.gov/drug/label.json?search=openfda.substance_name:%22HYDROXYZINE%20HYDROCHLORIDE%22&limit=1","label":"US label for hydroxyzine hydrochloride tablets, Dosage and Administration, via openFDA drug/label.json (effective 2026-06-03)","quote":"For symptomatic relief of anxiety and tension … adults, 50 to 100 mg q.i.d. … For … pruritus … adults, 25 mg t.i.d. or q.i.d. … As a sedative … 50 to 100 mg for adults","accessed":"2026-08-27"},{"id":"fda_hyd_ind","url":"https://api.fda.gov/drug/label.json?search=openfda.substance_name:%22HYDROXYZINE%20HYDROCHLORIDE%22&limit=1","label":"US label for hydroxyzine hydrochloride tablets, Indications and Usage, via openFDA","quote":"Useful in the management of pruritus due to allergic conditions such as chronic urticaria and atopic and contact dermatoses … As a sedative when used as a premedication and following general anesthesia","accessed":"2026-08-27"},{"id":"fda_hyd_contra","url":"https://api.fda.gov/drug/label.json?search=openfda.substance_name:%22HYDROXYZINE%20HYDROCHLORIDE%22&limit=1","label":"US label for hydroxyzine hydrochloride tablets, Contraindications, via openFDA","quote":"contraindicated in patients with known hypersensitivity to cetirizine hydrochloride or levocetirizine hydrochloride. Hydroxyzine is contraindicated in patients with a prolonged QT interval … hydroxyzine is contraindicated in early pregnancy.","accessed":"2026-08-27"},{"id":"fda_hyd_prec","url":"https://api.fda.gov/drug/label.json?search=openfda.substance_name:%22HYDROXYZINE%20HYDROCHLORIDE%22&limit=1","label":"US label for hydroxyzine hydrochloride tablets, Precautions, via openFDA","quote":"THE POTENTIATING ACTION OF HYDROXYZINE MUST BE CONSIDERED WHEN THE DRUG IS USED IN CONJUNCTION WITH CENTRAL NERVOUS SYSTEM DEPRESSANTS … Caution is recommended during the concomitant use of drugs known to prolong the QT interval","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:21.812539+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}