{"ok":true,"entry":{"slug":"green-coffee-bean","kind":"supplement","name":"green coffee bean extract","aliases":["chlorogenic acid"],"brands_sg":["Swanson Vitamins","Life Extension","Source Naturals","Nature's Craft"],"class":"botanical","tags":["general","energy"],"use_for":"marketed for weight loss · few trials, all poor quality","use_after":null,"use_duration":null,"take_with":null,"pros":["a 3-trial meta-analysis pooled 2.47 kg vs placebo","few safety concerns up to 200 mg/day for 12 weeks","unroasted beans carry more chlorogenic acid"],"cons":["ods calls all those trials poor methodological quality","one supporting trial was retracted after ftc criticism","contains caffeine — a stimulant hsa flags in annex b"],"dose_note":"the pooled trials gave 180 or 200 mg a day of green coffee bean extract for 4 to 12 weeks and averaged 2.47 kg more weight loss than placebo, but ods notes the methodological quality of every included study was poor and that a separate supporting trial was retracted by two of its three authors after the ftc criticised its design; green coffee beans contain caffeine unless a decaffeinated form is used, and caffeine is one of only four substances in hsa's annex b; no rda, ul, fda daily value or hsa singapore daily limit exists for green coffee bean extract or chlorogenic acid","dosage":{"ul":null,"unit":"mg","fda_dv":null,"rda_ai":null,"ul_status":"none_established","population":"general adult","hsa_max_daily":null},"ul_status":"none_established","sg_class":null,"cautions":["contains caffeine unless the decaffeinated form is used","reported adverse effects: headaches and urinary tract infections","safety has not been rigorously studied","green coffee is not in annex a or b; caffeine is annex b row 1"],"clashes":[{"src":["ods_wl_interactions_stimulants"],"note":"caffeine-containing ingredients could have an additive effect with other stimulants","with":"other stimulants"},{"src":["hsa_annexb_caffeine"],"food":true,"note":"HSA asks caffeine products to advise limiting concurrent tea and coffee","with":"other caffeine sources (tea, coffee)"}],"sources":[{"id":"ods_wl_gcb_table","url":"https://web.archive.org/web/20260826105104/https://ods.od.nih.gov/factsheets/WeightLoss-HealthProfessional/","label":"NIH ODS — Dietary Supplements for Weight Loss (Health Professional), updated 18 May 2022; read via the archive.org capture of 26 Aug 2026 because ods.od.nih.gov returns HTTP 403 to direct fetches — Table 1 summary row for green coffee bean extract","quote":"Green coffee bean extract … Few clinical trials, all of poor methodological quality … Research findings: Possible modest effect on body weight … Few safety concerns reported for up to 200 mg/day for as long as 12 weeks","accessed":"2026-08-27"},{"id":"ods_wl_gcb_mech","url":"https://web.archive.org/web/20260826105104/https://ods.od.nih.gov/factsheets/WeightLoss-HealthProfessional/","label":"NIH ODS — Dietary Supplements for Weight Loss (Health Professional), updated 18 May 2022; read via the archive.org capture of 26 Aug 2026 because ods.od.nih.gov returns HTTP 403 to direct fetches — why green beans differ from roasted, and caffeine content","quote":"Compared to roasted beans, green coffee beans have higher levels of chlorogenic acid … Green coffee beans contain caffeine (see section on caffeine above), although decaffeinated forms are available","accessed":"2026-08-27"},{"id":"ods_wl_gcb_meta","url":"https://web.archive.org/web/20260826105104/https://ods.od.nih.gov/factsheets/WeightLoss-HealthProfessional/","label":"NIH ODS — Dietary Supplements for Weight Loss (Health Professional), updated 18 May 2022; read via the archive.org capture of 26 Aug 2026 because ods.od.nih.gov returns HTTP 403 to direct fetches — Onakpoya meta-analysis of three trials","quote":"Onakpoya and colleagues conducted a meta-analysis of three trials in which participants who were overweight received either 180 or 200 mg/day green coffee bean extract for 4 to 12 weeks … mean weight loss of 2.47 kg more than placebo","accessed":"2026-08-27"},{"id":"ods_wl_gcb_retraction","url":"https://web.archive.org/web/20260826105104/https://ods.od.nih.gov/factsheets/WeightLoss-HealthProfessional/","label":"NIH ODS — Dietary Supplements for Weight Loss (Health Professional), updated 18 May 2022; read via the archive.org capture of 26 Aug 2026 because ods.od.nih.gov returns HTTP 403 to direct fetches — the retracted trial","quote":"the study was strongly criticized by the FTC for having several critical flaws in its design. Two of the three study authors subsequently retracted the journal publication","accessed":"2026-08-27"},{"id":"ods_wl_gcb_safety","url":"https://web.archive.org/web/20260826105104/https://ods.od.nih.gov/factsheets/WeightLoss-HealthProfessional/","label":"NIH ODS — Dietary Supplements for Weight Loss (Health Professional), updated 18 May 2022; read via the archive.org capture of 26 Aug 2026 because ods.od.nih.gov returns HTTP 403 to direct fetches — tolerability and stimulant effect","quote":"Green coffee bean extract appears to be well tolerated, but its safety has not been rigorously studied. Reported adverse effects include headaches and urinary tract infections. The caffeine naturally present in green coffee beans acts as a stimulant","accessed":"2026-08-27"},{"id":"ods_wl_caffeine","url":"https://web.archive.org/web/20260826105104/https://ods.od.nih.gov/factsheets/WeightLoss-HealthProfessional/","label":"NIH ODS — Dietary Supplements for Weight Loss (Health Professional), updated 18 May 2022; read via the archive.org capture of 26 Aug 2026 because ods.od.nih.gov returns HTTP 403 to direct fetches — caffeine section — basis for the 'energy' tag","quote":"Caffeine is a methylxanthine that stimulates the central nervous system, heart, and skeletal muscles … Caffeine increases thermogenesis in a linear, dose-dependent fashion in humans","accessed":"2026-08-27"},{"id":"ods_wl_interactions_stimulants","url":"https://web.archive.org/web/20260826105104/https://ods.od.nih.gov/factsheets/WeightLoss-HealthProfessional/","label":"NIH ODS — Dietary Supplements for Weight Loss (Health Professional), updated 18 May 2022; read via the archive.org capture of 26 Aug 2026 because ods.od.nih.gov returns HTTP 403 to direct fetches — interactions section","quote":"Other ingredients, such as caffeine and bitter orange, could have an additive effect if taken with other stimulants.","accessed":"2026-08-27"},{"id":"hsa_annexb_caffeine","url":"https://file.go.gov.sg/hsa-chp-prohibited-restricted-ing-guidelines.pdf","label":"HSA Singapore — Guidelines on Prohibited and Restricted Ingredients in Health Supplements and Traditional Medicines, GL-CHPB-1-012 Rev. No. 001 (October 2025) — Annex B row 1, caffeine — green coffee bean extract is not itself listed, but the beans contain caffeine, which is one of Annex B's four substances","quote":"Caffeine — Known to have stimulatory effects. Excessive use may cause nervousness, irritability, sleep disturbances, diuresis, increased blood pressure, heart rate and gastrointestinal disturbances.","accessed":"2026-08-27"},{"id":"hsa_prohibited","url":"https://file.go.gov.sg/hsa-chp-prohibited-restricted-ing-guidelines.pdf","label":"HSA Singapore — Guidelines on Prohibited and Restricted Ingredients in Health Supplements and Traditional Medicines, GL-CHPB-1-012 Rev. No. 001 (October 2025) — Annex A (118 rows) and Annex B (4 rows): green coffee bean extract / Coffea arabica, canephora, robusta / chlorogenic acid is NOT LISTED in either; Annex A runs 30. Coenzyme Q10 then 31. Colchicum autumnale, with no Coffea between them","quote":"The objective of this guideline is to highlight the substances of concern when used in HS and TM and is not meant to be an exhaustive list.","accessed":"2026-08-27"},{"id":"hsa_hs_guidelines","url":"https://file.go.gov.sg/hsa-hs-guidelines.pdf","label":"HSA Singapore — Health Supplements Guidelines GL-CHPB-3-001 (January 2026), clause 4.8 with Tables 4–5, which list vitamins and minerals only — no botanical or fibre rows","quote":"4.8 HS for use by the general adult population should not contain vitamins and minerals exceeding the stipulated limits stated in Tables 4 and 5.","accessed":"2026-08-27"},{"id":"iherb_sg","url":"https://sg.iherb.com/c/green-coffee-bean-extract","label":"iHerb Singapore — Green Coffee Bean Extract category page, default listing order, 27 Aug 2026","quote":"1 - 6 of 6 results: Swanson Vitamins, Full Spectrum Green Coffee Bean; Life Extension, CoffeeGenic Green Coffee Extract; Swanson Vitamins, Green Coffee Bean Extract; Source Naturals, Green Coffee Extract; Nature's Craft, Green Coffee Bean Extract","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:21.812539+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}