{"ok":true,"entry":{"slug":"glyceryl-trinitrate","kind":"medication","name":"glyceryl trinitrate","aliases":["nitroglycerin","GTN","Nitrolingual"],"brands_sg":["Glytrin","Myonit Insta","Rectogesic","Glyceryl Trinitrate-Hameln","Glydex IV"],"class":"nitrate","tags":["heart-bp"],"use_for":"healthhub: to relieve and to prevent angina attacks","use_after":"healthhub: at the first sign of an attack, not later","use_duration":null,"take_with":"healthhub: under the tongue · the spray is not inhaled","pros":["healthhub: relief usually comes within five minutes","hsa: sg spray and sublingual tablet are pharmacy-only","nhs: also works taken before exertion, 1–3 min"],"cons":["healthhub: headache, flushing, dizziness on standing","healthhub: sg tablets binned 2 months after opening","healthhub: with sildenafil-type drugs, bp can crash"],"dose_note":"no singapore dosing text is published: the ndf product pages for both pharmacy-only sg products — glytrin spray (SIN09161P) and myonit insta sublingual tablets 0.5 mg (SIN15702P) — carry a product-information block only, with no indication or dosing section, so NO SG LABEL MAXIMUM WAS READ. the uk nhs page states \"Do not use more than 2 doses during an angina attack. 1 dose is either 1 tablet or 1 to 2 sprays\" and says to call 999 if pain persists 5 minutes after the second dose. singapore's healthhub leaflet describes a different ceiling — a third tablet or spray after another five minutes, then \"seek medical help or call for an ambulance (995) immediately\". in singapore the pharmacist or doctor sets the dose.","dosage":null,"ul_status":null,"sg_class":"pharmacy-only","cautions":["allergy to gtn or to the product's other ingredients (healthhub)","pregnancy, planning pregnancy or breastfeeding (healthhub)","regular users — healthhub warns that stopping suddenly can bring attacks on","chest pain that does not settle — healthhub points to 995, not a further dose"],"clashes":[{"src":["hh_gtn_avoid"],"note":"healthhub: blood pressure can drop greatly; deaths have been reported with sildenafil and nitrates","with":"sildenafil, tadalafil or vardenafil"},{"src":["hh_gtn_side"],"food":true,"note":"healthhub: dizziness and faintness are more likely, as they are on standing or in the heat","with":"alcohol"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg dataset d_767279312753558cbf19d48344577084), Forensicclassification column; all 5,511 rows cached at /tmp/hsa_all.json and filtered locally (never re-fetched), 5 glyceryl trinitrate / nitroglycerin rows, 27 Aug 2026","quote":"GLYTRIN SPRAY SIN09161P (400 mcg/spray) and MYONIT INSTA NITROGLYCERIN SUBLINGUAL TABLETS 0.5mg SIN15702P read \"Pharmacy Only\"; RECTOGESIC OINTMENT 0.2% SIN12240P, GLYCERYL TRINITRATE-HAMELN INJECTION SIN15105P and GLYDEX IV SIN15510P read \"Prescription Only\"","accessed":"2026-08-27"},{"id":"ndf_glytrin_class","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin09161p/","label":"MOH National Drug Formulary — GLYTRIN SPRAY [SIN09161P], Product information block (no Indication or Dosing section is published for this licence)","quote":"Active Ingredient and Strength: GLYCERYL TRINITRATE - 400 MCG/SPRAY · Forensic Classification: PHARMACY ONLY MEDICINES · Anatomical Therapeutic Chemical (ATC) code C01DA02","accessed":"2026-08-27"},{"id":"ndf_myonit_class","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin15702p/","label":"MOH National Drug Formulary — MYONIT INSTA NITROGLYCERIN SUBLINGUAL TABLETS USP 0.5MG [SIN15702P], Product information block (no Indication or Dosing section is published for this licence)","quote":"DILUTED NITROGLYCERIN USP 5 MG EQV NITROGLYCERIN - 0.5 MG · Forensic Classification: PHARMACY ONLY MEDICINES · Anatomical Therapeutic Chemical (ATC) code C01DA02","accessed":"2026-08-27"},{"id":"hh_gtn_uses","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/glyceryl-trinitrate","label":"HealthHub (National Medication Information workgroup / Pharmaceutical Society of Singapore) — Glyceryl Trinitrate: what is this medication for","quote":"Glyceryl trinitrate (GTN) belongs to a class of medications called Nitrates. Nitrates are used to prevent and treat the symptoms of angina (chest pain) … Nitrates work by relaxing blood vessels","accessed":"2026-08-27"},{"id":"hh_gtn_howto","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/glyceryl-trinitrate","label":"HealthHub — Glyceryl Trinitrate: how should I take or use this medication","quote":"The tablet or spray should be used at the first sign of an attack of angina … usually provides relief within five minutes … If you still have pain after using the third tablet … call for an ambulance (995)","accessed":"2026-08-27"},{"id":"hh_gtn_admin","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/glyceryl-trinitrate","label":"HealthHub — Glyceryl Trinitrate: directions for the sublingual tablets and the mouth spray","quote":"Place a tablet under your tongue when you experience chest pain. Do not swallow the tablet … point the nozzle at the area under your tongue … do NOT inhale the spray.","accessed":"2026-08-27"},{"id":"hh_gtn_prec","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/glyceryl-trinitrate","label":"HealthHub — Glyceryl Trinitrate: what precautions should I take, and stopping","quote":"You are allergic to this medication or any of the other ingredients … pregnant, planning to become pregnant, or breastfeeding … Stopping your medication suddenly may cause angina attacks.","accessed":"2026-08-27"},{"id":"hh_gtn_side","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/glyceryl-trinitrate","label":"HealthHub — Glyceryl Trinitrate: common side effects","quote":"Dizziness, lightheadedness or faintness … more likely to happen if you drink alcohol, stand for a long period of time, exercise or when the weather is hot … Temporary headache … Flushing … Fast heartbeat. Nausea and Vomiting","accessed":"2026-08-27"},{"id":"hh_gtn_store","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/glyceryl-trinitrate","label":"HealthHub — Glyceryl Trinitrate: how should I store this medication","quote":"Label the bottle with the opening date when you first open it. Throw the bottle away two months after the date of opening, even if you still have tablets left.","accessed":"2026-08-27"},{"id":"hh_gtn_avoid","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/glyceryl-trinitrate","label":"HealthHub — Glyceryl Trinitrate: what food or medication should I avoid","quote":"When Sildenafil, Tadalafil or Vardenafil is taken with Nitrates, your blood pressure can lower greatly, resulting in dizziness, lightheadedness or fainting. In some cases, death has been reported when Sildenafil was taken with Nitrates.","accessed":"2026-08-27"},{"id":"nhs_gtn_hub","url":"https://www.nhs.uk/medicines/glyceryl-trinitrate-gtn/","label":"NHS medicines A–Z — Glyceryl trinitrate (GTN) (hub page)","quote":"Glyceryl trinitrate (GTN) - Brand names: Rectogesic, Minitran, Glytrin. Find out how glyceryl trinitrate (GTN) treats angina (chest pain) and anal fissures and how to take it.","accessed":"2026-08-27"},{"id":"nhs_gtn_how","url":"https://www.nhs.uk/medicines/glyceryl-trinitrate-gtn/how-and-when-to-take-glyceryl-trinitrate-gtn/","label":"NHS medicines A–Z — Glyceryl trinitrate (GTN): how and when to take it","quote":"Do not use more than 2 doses during an angina attack. 1 dose is either 1 tablet or 1 to 2 sprays … 1 tablet under your tongue before you start your activity … 1 to 3 minutes to work.","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:21.812539+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}