{"ok":true,"entry":{"slug":"glipizide","kind":"medication","name":"glipizide","aliases":["Minidiab"],"brands_sg":["Minidiab","Dibizide","Diacon","Glynase","Diactin"],"class":"sulfonylurea","tags":["diabetes"],"use_for":"prescribed for diabetes alongside diet and exercise","use_after":"healthhub: immediately before meals, as the doctor directs","use_duration":null,"take_with":"meals · healthhub: meals should not be missed or delayed","pros":["healthhub: helps the pancreas release more insulin","hh: works with diet and exercise on blood sugar","hsa: 7 registered brands, all 5 mg tablets"],"cons":["healthhub: low blood sugar is a common side effect","healthhub: weight gain is common","hh: alcohol can cause flushing, nausea, fast heartbeat"],"dose_note":"the us fda label for immediate-release glipizide tablets states 'The maximum recommended once daily dose is 15 mg' and 'The maximum recommended total daily dose is 40 mg'; the extended-release glucotrol xl label instead states 'The maximum recommended dose is 20 mg once daily'. every glipizide product registered in singapore is a 5 mg immediate-release tablet, so the 40 mg/day figure is the relevant label ceiling for the sg dosage form. in singapore the prescriber sets the dose.","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["g6pd deficiency, or a sulfa allergy (healthhub)","heart, kidney or liver problems (healthhub)","pregnancy, planning pregnancy or breastfeeding (healthhub)","over 65 — healthhub: higher risk of side effects"],"clashes":[{"src":["hh_glip_avoid"],"food":true,"note":"healthhub: may cause flushing, nausea, vomiting, headache, fast heartbeat, fast breathing and giddiness","with":"alcohol"},{"src":["fda_glipizide_dose"],"note":"fda label: glipizide peak concentration and total exposure are reduced when co-administered","with":"colesevelam"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached in full and filtered locally)","quote":"All 7 registered glipizide products are 5 mg tablets with Forensicclassification 'Prescription Only' — SIN04059P MINIDIAB · SIN10183P DIBIZIDE · SIN12348P DIACON · SIN08508P GLYNASE · SIN13084P DIACTIN · SIN10440P BEAPIZIDE","accessed":"2026-08-27"},{"id":"hh_glip_uses","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/glipizide","label":"HealthHub (National Medication Information workgroup, SG) — Glipizide: what is this medication for","quote":"Glipizide is used in the treatment of diabetes. It works together with lifestyle changes such as having a healthy diet and regular exercise … It helps the pancreas to release more insulin to bring your blood sugar levels down.","accessed":"2026-08-27"},{"id":"hh_glip_howto","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/glipizide","label":"HealthHub — Glipizide: how should I take this medication","quote":"Take the tablet(s) as directed by your doctor immediately before meal(s). Do not miss or delay meals after taking the medication.","accessed":"2026-08-27"},{"id":"hh_glip_side","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/glipizide","label":"HealthHub — Glipizide: common side effects","quote":"The common side effects of Glipizide include: Low blood sugar (hypoglycemia) … Weight gain … Symptoms of low blood sugar include: Weakness, Dizziness, Hunger, Sweating, Trembling, Blurred vision","accessed":"2026-08-27"},{"id":"hh_glip_precautions","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/glipizide","label":"HealthHub — Glipizide: what precautions should I take","quote":"Have Glucose-6 Phosphate Dehydrogenase (G6PD) deficiency … Are allergic to sulfonamide drugs such as sulfamethoxazole or have a 'sulfa' allergy … Have heart, kidney or liver problems … Are an elderly above 65 years old","accessed":"2026-08-27"},{"id":"hh_glip_avoid","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/glipizide","label":"HealthHub — Glipizide: what food or medication should I avoid","quote":"Avoid taking alcohol with this medication as it may cause symptoms such as flushing, nausea, vomiting, headache, fast heartbeat, fast breathing and giddiness.","accessed":"2026-08-27"},{"id":"fda_glipizide_dose","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22GLIPIZIDE%22+AND+dosage_and_administration:%22maximum+recommended+total+daily+dose%22&limit=1","label":"US FDA label for glipizide tablets (immediate release), DOSAGE AND ADMINISTRATION, via openFDA (Bryant Ranch Prepack, effective 2026-03-19)","quote":"The maximum recommended once daily dose is 15 mg. The maximum recommended total daily dose is 40 mg … When colesevelam is co-administered with glipizide, maximum plasma concentration and total exposure to glipizide is reduced.","accessed":"2026-08-27"},{"id":"fda_glucotrol_xl_dose","url":"https://api.fda.gov/drug/label.json?search=openfda.brand_name:%22GLUCOTROL%22&limit=1","label":"US FDA label for GLUCOTROL XL (glipizide extended release), section 2 Dosage and Administration, via openFDA (Roerig, effective 2026-07-21)","quote":"The maximum recommended dose is 20 mg once daily.","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:19.87501+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}