{"ok":true,"entry":{"slug":"glimepiride","kind":"medication","name":"glimepiride","aliases":["Amaryl"],"brands_sg":["Amaryl","Dialosa"],"class":"sulfonylurea","tags":["diabetes"],"use_for":"us label: type 2 diabetes, with diet and exercise","use_after":"healthhub: immediately before a meal, meals not delayed","use_duration":null,"take_with":"healthhub: the first main meal of the day · no alcohol","pros":["healthhub: helps the pancreas release more insulin","us label: one dose a day, with the first meal","sg register lists 2 mg and 3 mg tablets"],"cons":["healthhub: low blood sugar and weight gain are common","healthhub: over-65s have a higher risk of side effects","healthhub: alcohol can cause flushing and nausea"],"dose_note":"no singapore package insert was read. the us glimepiride label states \"Recommended starting dose is 1 or 2 mg once daily … Maximum recommended dose is 8 mg once daily. Administer with breakfast or first meal of the day\" — 8 mg once daily is the adult label maximum, and the same label adds \"Use 1 mg starting dose and titrate slowly in patients at increased risk for hypoglycemia (e.g., elderly, patients with renal impairment)\". the sg register carries only 2 mg and 3 mg tablets. in singapore the prescriber sets the dose.","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["g6pd deficiency, or a sulfonamide (\"sulfa\") allergy — healthhub asks that this be declared","heart, kidney or liver problems (healthhub)","pregnant, planning pregnancy or breastfeeding (healthhub)","over 65, eating less than usual, or exercising more than usual (healthhub)"],"clashes":[{"src":["hh_glim_avoid"],"food":true,"note":"healthhub: it may cause flushing, nausea, vomiting, headache, fast heartbeat and giddiness","with":"alcohol"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg dataset d_767279312753558cbf19d48344577084), Forensicclassification column; all 5,511 rows cached at /tmp/hsa_all.json and filtered locally (not re-fetched), glimepiride rows, 27 Aug 2026","quote":"AMARYL 2.0 TABLETS 2 mg SIN10459P · DIALOSA TABLET 2MG SIN13675P · DIALOSA TABLET 3MG SIN13674P — ATC A10BB12; all 3 glimepiride rows read Forensicclassification \"Prescription Only\"","accessed":"2026-08-27"},{"id":"hh_glim_uses","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/glimepiride","label":"HealthHub (Pharmaceutical Society of Singapore / MOH) — Glimepiride: what is this medication for","quote":"Glimepiride is used in the treatment of diabetes … It helps the pancreas to release more insulin to bring your blood sugar levels down.","accessed":"2026-08-27"},{"id":"hh_glim_howto","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/glimepiride","label":"HealthHub — Glimepiride: how should I take or use this medication","quote":"Take the tablet(s) as directed by your doctor immediately before meal(s). Do not miss or delay meals after taking the medication.","accessed":"2026-08-27"},{"id":"hh_glim_prec","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/glimepiride","label":"HealthHub — Glimepiride: what precautions should I take","quote":"Have Glucose-6 Phosphate Dehydrogenase (G6PD) deficiency … Are allergic to sulfonamide drugs … Have heart, kidney or liver problems … Are an elderly above 65 years old as you have a higher risk of having side effects","accessed":"2026-08-27"},{"id":"hh_glim_side","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/glimepiride","label":"HealthHub — Glimepiride: common side effects","quote":"The common side effects of Glimepiride include: Low blood sugar (hypoglycemia) … Weight gain … Symptoms of low blood sugar include: Weakness, Dizziness, Hunger, Sweating, Trembling, Blurred vision","accessed":"2026-08-27"},{"id":"hh_glim_avoid","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/glimepiride","label":"HealthHub — Glimepiride: what food or medication should I avoid","quote":"Avoid taking alcohol with this medication as it may cause symptoms such as flushing, nausea, vomiting, headache, fast heartbeat, fast breathing and giddiness.","accessed":"2026-08-27"},{"id":"fda_glim_dose","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22glimepiride%22&limit=5","label":"US label for glimepiride tablets (American Health Packaging, effective 2024-11-13) via openFDA drug/label.json, section 2 Dosage and Administration","quote":"Recommended starting dose is 1 or 2 mg once daily … Maximum recommended dose is 8 mg once daily. Administer with breakfast or first meal of the day.","accessed":"2026-08-27"},{"id":"fda_glim_dose2","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22glimepiride%22&limit=5","label":"US label for glimepiride tablets — section 2.1 Recommended Dosing, via openFDA drug/label.json","quote":"Use 1 mg starting dose and titrate slowly in patients at increased risk for hypoglycemia (e.g., elderly, patients with renal impairment).","accessed":"2026-08-27"},{"id":"fda_glim_ind","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22glimepiride%22&limit=5","label":"US label for glimepiride tablets — section 1 Indications and Usage, via openFDA drug/label.json","quote":"Glimepiride tablets are indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus … a sulfonylurea … should not be used for the treatment of type 1 diabetes mellitus","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:19.87501+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}