{"ok":true,"entry":{"slug":"gabapentin","kind":"medication","name":"gabapentin","aliases":["Neurontin"],"brands_sg":["Neurontin","Neuran","Alpentin","Gabapin"],"class":"anticonvulsant / neuropathic agent","tags":["other","pain-fever"],"use_for":"prescribed for nerve pain and for seizures","use_after":"with or without food · nhs: doses spaced through the day","use_duration":null,"take_with":"water or juice · nhs: capsules swallowed whole","pros":["healthhub: used for nerve pain and for seizures","healthhub: may be taken with or without food","sg register: 100, 300 and 400 mg capsules"],"cons":["healthhub: drowsiness, dizziness, swelling, fatigue","fda: opioids — respiratory depression, deaths reported","nhs: stopping suddenly can bring withdrawal or fits"],"dose_note":"the nhs gives a usual adult range of '900mg to 3,600mg a day, split into 3 doses' for nerve pain. the us fda label for neurontin says the dose 'can subsequently be titrated up as needed for pain relief to a dose of 1800 mg/day' in postherpetic neuralgia, and for epilepsy that 'Dosages up to 2400 mg/day have been administered in long-term clinical studies. Doses of 3600 mg/day have also been administered to a small number of patients'. sg-registered capsules are 100, 300 and 400 mg. in singapore the prescriber sets the dose, as directed on the label or by your pharmacist or doctor.","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["a kidney condition, myasthenia gravis or a mental health condition; pregnant, planning a pregnancy or breastfeeding (healthhub)","breathing already impaired, or also on an opioid or another cns depressant (fda label)","a history of drug abuse — fda label: misuse and self-dose escalation are reported","on it a while — nhs: the dose is reduced gradually, not stopped"],"clashes":[{"src":["fda_neurontin_opioid","nhs_gaba_other"],"note":"fda label: respiratory depression and sedation, sometimes resulting in death, have been reported with gabapentin; nhs: very tired and dizzy when gabapentin is started","with":"opioids (morphine, oxycodone, buprenorphine)"},{"src":["fda_neurontin_resp","nhs_gaba_other"],"note":"fda label: serious, life-threatening or fatal respiratory depression when coadministered with cns depressants; the nhs also names antidepressants and antipsychotics","with":"other cns depressants and sedating medicines"},{"src":["hh_gaba_food"],"food":true,"note":"healthhub: can cause excessive drowsiness","with":"alcohol"},{"src":["hh_gaba_food"],"note":"healthhub: taken at least two hours apart, as they may reduce how much gabapentin is absorbed","with":"antacids"},{"src":["nhs_gaba_herbal"],"note":"nhs: ones that can make you feel dizzy or drowsy could make these side effects worse","with":"sedating herbal remedies and supplements"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, filtered locally for gabapentin)","quote":"All 12 registered gabapentin products carry Forensicclassification 'Prescription Only', in 100, 300 and 400 mg capsules — SIN08303P NEURONTIN CAPSULE 300 mg; SIN15230P NEURAN CAPSULE 300MG; SIN16698P ALPENTIN CAPSULE 100MG; SIN16294P GABAPIN 100","accessed":"2026-08-27"},{"id":"hh_gaba_uses","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/gabapentin","label":"HealthHub (Pharmaceutical Society of Singapore) — Gabapentin: what is this medication for","quote":"Gabapentin is used for treatment of neuropathic (nerve) pain ... Gabapentin may also be used in the treatment of seizures (fits).","accessed":"2026-08-27"},{"id":"hh_gaba_admin","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/gabapentin","label":"HealthHub — Gabapentin: how should I take or use this medication","quote":"Gabapentin may be taken with or without food. For gabapentin capsules, swallow whole, do not crush or chew it. Do not stop taking your medication without checking with your healthcare professional.","accessed":"2026-08-27"},{"id":"hh_gaba_side","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/gabapentin","label":"HealthHub — Gabapentin: common side effects","quote":"Common side effects of gabapentin include: Nausea ... Drowsiness ... Dizziness ... Swelling of hands or legs; Fatigue (Feeling of tiredness); Muscle weakness","accessed":"2026-08-27"},{"id":"hh_gaba_rare","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/gabapentin","label":"HealthHub — Gabapentin: rare but serious side effects","quote":"Other serious side effects include: Blurring of your vision or loss of vision; Worsening agitation, restlessness or violent behaviour","accessed":"2026-08-27"},{"id":"hh_gaba_prec","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/gabapentin","label":"HealthHub — Gabapentin: what precautions should I take","quote":"You have a history of: Kidney condition; Myasthenia Gravis (an immune disease that causes muscle weakness); Mental health conditions; You are pregnant, planning to become pregnant, or breastfeeding","accessed":"2026-08-27"},{"id":"hh_gaba_food","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/gabapentin","label":"HealthHub — Gabapentin: what food or medication should I avoid","quote":"Avoid drinking alcohol while taking gabapentin as it can cause excessive drowsiness. Take antacids at least two hours apart from gabapentin, as they may reduce the amount of medication being taken up by your body.","accessed":"2026-08-27"},{"id":"nhs_gaba_how","url":"https://www.nhs.uk/medicines/gabapentin/how-and-when-to-take-gabapentin/","label":"NHS Medicines A-Z — Gabapentin: how and when to take it","quote":"Gabapentin is a prescription medicine ... Swallow gabapentin capsules and tablets whole with a drink of water or juice. Do not chew them ... Try to space your doses evenly through the day.","accessed":"2026-08-27"},{"id":"nhs_gaba_dose","url":"https://www.nhs.uk/medicines/gabapentin/how-and-when-to-take-gabapentin/","label":"NHS Medicines A-Z — Gabapentin: dosage for nerve pain","quote":"The usual dose to treat nerve pain in adults is 900mg to 3,600mg a day, split into 3 doses.","accessed":"2026-08-27"},{"id":"nhs_gaba_stop","url":"https://www.nhs.uk/medicines/gabapentin/how-and-when-to-take-gabapentin/","label":"NHS Medicines A-Z — Gabapentin: stopping gabapentin","quote":"Stopping gabapentin suddenly can cause seizures that will not stop ... you may have severe withdrawal symptoms, including: anxiety; difficulty sleeping; feeling sick; pain; sweating","accessed":"2026-08-27"},{"id":"fda_neurontin_dose","url":"https://api.fda.gov/drug/label.json?search=openfda.brand_name:%22NEURONTIN%22&limit=1","label":"US FDA label for NEURONTIN (gabapentin), section 2 Dosage and Administration, via openFDA drug/label.json (effective 2026-05-12)","quote":"The dose can subsequently be titrated up as needed for pain relief to a dose of 1800 mg/day ... Dosages up to 2400 mg/day have been administered in long-term clinical studies. Doses of 3600 mg/day have also been administered","accessed":"2026-08-27"},{"id":"nhs_gaba_other","url":"https://www.nhs.uk/medicines/gabapentin/taking-gabapentin-with-other-medicines-and-herbal-supplements/","label":"NHS Medicines A-Z — Gabapentin: cautions with other medicines","quote":"strong painkillers, such as morphine – these can make you very tired and dizzy when you start taking gabapentin ... antidepressants, such as amitriptyline or fluoxetine ... antipsychotic medicines for mental health problems ...","accessed":"2026-08-27"},{"id":"nhs_gaba_herbal","url":"https://www.nhs.uk/medicines/gabapentin/taking-gabapentin-with-other-medicines-and-herbal-supplements/","label":"NHS Medicines A-Z — Gabapentin: mixing gabapentin with herbal remedies or supplements","quote":"Taking herbal remedies and supplements that can make you feel dizzy or drowsy while you're taking gabapentin could make these side effects worse.","accessed":"2026-08-27"},{"id":"fda_neurontin_opioid","url":"https://api.fda.gov/drug/label.json?search=openfda.brand_name:%22NEURONTIN%22&limit=1","label":"US FDA label for NEURONTIN (gabapentin), section 7.1 Opioids, via openFDA drug/label.json (effective 2026-05-12)","quote":"Respiratory depression and sedation, sometimes resulting in death, have been reported following coadministration of gabapentin with opioids (e.g., morphine, hydrocodone, oxycodone, buprenorphine)","accessed":"2026-08-27"},{"id":"fda_neurontin_resp","url":"https://api.fda.gov/drug/label.json?search=openfda.brand_name:%22NEURONTIN%22&limit=1","label":"US FDA label for NEURONTIN (gabapentin), section 5.8 Respiratory Depression, via openFDA drug/label.json (effective 2026-05-12)","quote":"There is evidence from case reports, human studies, and animal studies associating gabapentin with serious, life-threatening, or fatal respiratory depression when coadministered with CNS depressants, including opioids, or in the setting of underlying respiratory impairment.","accessed":"2026-08-27"},{"id":"fda_neurontin_abuse","url":"https://api.fda.gov/drug/label.json?search=openfda.brand_name:%22NEURONTIN%22&limit=1","label":"US FDA label for NEURONTIN (gabapentin), section 9.2 Abuse, via openFDA drug/label.json (effective 2026-05-12)","quote":"Gabapentin misuse and abuse have been reported in the postmarketing setting and published literature. Most of the individuals described in these reports had a history of polysubstance abuse.","accessed":"2026-08-27"},{"id":"fda_neurontin_dependence","url":"https://api.fda.gov/drug/label.json?search=openfda.brand_name:%22NEURONTIN%22&limit=1","label":"US FDA label for NEURONTIN (gabapentin), section 9.3 Dependence, via openFDA drug/label.json (effective 2026-05-12)","quote":"After discontinuation of short-term and long-term treatment with gabapentin, withdrawal symptoms have been observed in some patients. Withdrawal symptoms may occur shortly after discontinuation, usually within 48 hours.","accessed":"2026-08-27"},{"id":"fda_neurontin_cs","url":"https://api.fda.gov/drug/label.json?search=openfda.brand_name:%22NEURONTIN%22&limit=1","label":"US FDA label for NEURONTIN (gabapentin), section 9.1 Controlled Substance, via openFDA drug/label.json (effective 2026-05-12) — cited in verify_notes only, US federal scheduling, not SG","quote":"NEURONTIN contains gabapentin, which is not a controlled substance.","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:19.87501+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}