{"ok":true,"entry":{"slug":"fedac","kind":"medication","name":"fedac (brand)","aliases":["pseudoephedrine hcl 60 mg + triprolidine hcl 2.5 mg (tablet)","pseudoephedrine hcl 30 mg + triprolidine hcl 1.25 mg per 5 ml (syrup)","triprolidine/pseudoephedrine"],"brands_sg":["Fedac (Teva)"],"class":"antihistamine + decongestant","tags":["cold-flu","allergy"],"use_for":"blocked nose, cold, sinus and allergy symptoms per label","use_after":"3 times a day per label · not too close to bedtime","use_duration":null,"take_with":"with or without food (healthhub) · label is silent on food","pros":["covers runny nose, sneezing and blocked nose together","no prescription needed — pharmacist-supplied (p class)","tablet or syrup — both hsa-registered strengths"],"cons":["drowsiness — label: no driving or machinery if affected","label: dry mouth, restlessness, trouble in sleeping","label bars severe hypertension/severe coronary disease"],"dose_note":"label: adults 1 tablet 3 times a day, or 2 teaspoonfuls (10 ml) of syrup 3 times a day; nhs frames pseudoephedrine as short-term use, usually up to 5 to 7 days; as directed on the label or by your pharmacist","dosage":null,"ul_status":null,"sg_class":"pharmacy-only","cautions":["high blood pressure, heart disease or overactive thyroid — ask a pharmacist first; severe hypertension, severe coronary artery disease or hyperthyroidism: label says do not use","diabetes, glaucoma, prostate or bladder trouble, liver or kidney problems — ask a pharmacist first","maois now or within the last 2 weeks — label says do not use","pregnant or breastfeeding — ask first; label: 'no specific data' in pregnancy · under 2: label says not to be used"],"clashes":[{"src":["sg_leaflet","healthhub_trip"],"note":"label: do not use with or within 2 weeks of maois — may cause a rise in blood pressure","with":"maois (e.g. moclobemide, selegiline)"},{"src":["sg_leaflet","nhs_pse_interact"],"note":"label: may cause a rise in blood pressure; nhs: avoid other medicines for a blocked nose","with":"other decongestants / sympathomimetics (e.g. xylometazoline, oxymetazoline nasal sprays)"},{"src":["sg_leaflet","nhs_pse_interact"],"note":"label: pseudoephedrine may reverse the hypotensive effect; nhs: check with a pharmacist or doctor","with":"blood pressure medicines (e.g. beta blockers, methyldopa)"},{"src":["sg_leaflet","healthhub_trip"],"food":true,"note":"label: triprolidine may enhance the drowsiness caused by sedative drugs and alcohol","with":"alcohol"},{"src":["sg_leaflet","healthhub_trip"],"note":"label: triprolidine may enhance the drowsiness caused by sedative drugs and alcohol","with":"sedatives and sleeping tablets"},{"src":["nhs_pse_interact"],"note":"nhs: check with a pharmacist or doctor before combining with pseudoephedrine","with":"tricyclic antidepressants, digoxin, ergot alkaloids (e.g. ergotamine)"}],"sources":[{"id":"ndf_fedac_tab","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin03116p/","label":"MOH National Drug Formulary — FEDAC TABLET [SIN03116P] (HSA-registered product record)","quote":"PSEUDOEPHEDRINE HCL - 60 MG … TRIPROLIDINE HCL - 2.5 MG … TABLET … PHARMACY ONLY MEDICINES … TEVA PHARMACEUTICAL INVESTMENTS SINGAPORE PTE. LTD. … PT ACTAVIS INDONESIA - INDONESIA REP OF … R01BA52","accessed":"2026-08-27"},{"id":"ndf_fedac_syr","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin03193p/","label":"MOH National Drug Formulary — FEDAC SYRUP [SIN03193P] (HSA-registered product record + clinical info)","quote":"PSEUDOEPHEDRINE HCL - 30 MG/5 ML … TRIPROLIDINE HCL - 1.25 MG/5 ML … SYRUP … PHARMACY ONLY MEDICINES … nasal and respiratory congestion, common cold, acute sinusitis, allergic rhinitis … 2 teaspoonfuls 3 times a day … 1 teaspoonful is equal to 5ml … severe hypertension or severe coronary artery disease … hyperthyroidism","accessed":"2026-08-27"},{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (official open dataset on data.gov.sg, managed by HSA, last updated 7 Aug 2026; same register as HSA Infosearch)","quote":"SIN03116P · FEDAC TABLET · PSEUDOEPHEDRINE HCl&&TRIPROLIDINE HCl · 60 mg&&2.5 mg · TABLET · Pharmacy Only · TEVA PHARMACEUTICAL INVESTMENTS SINGAPORE PTE. LTD. · PT ACTAVIS INDONESIA — SIN03193P · FEDAC SYRUP · PSEUDOEPHEDRINE HCl&&TRIPROLIDINE HCl · 30 mg/5 ml&&1.25 mg/5 ml · SYRUP · Pharmacy Only · TEVA PHARMACEUTICAL INVESTMENTS SINGAPORE PTE. LTD. · PT ACTAVIS INDONESIA","accessed":"2026-08-27"},{"id":"sg_leaflet","url":"https://drlesliekoh.com.sg/wp-content/uploads/2023/03/3845841.pdf","label":"Fedac Tablet and Syrup — Singapore package leaflet (Teva / PT Actavis Indonesia, rev. Sept 2020; PDF copy hosted by drlesliekoh.com.sg)","quote":"Triprolidine HCl BP 2.5mg/tablet … Pseudoephedrine HCl BP 60mg/tablet … Triprolidine HCl BP 1.25mg/5ml … Pseudoephedrine HCl BP 30mg/5ml … Symptomatic treatment of nasal and respiratory congestion, common cold, acute sinusitis, allergic rhinitis … Tablet : Adults : 1 tablet 3 times a day … patients with severe hypertension or severe coronary artery disease; patients who are taking or have taken MAOIs within the preceding 2 weeks; patients with hyperthyroidism … Triprolidine may cause drowsiness. If affected do not drive or operate machinery … Triprolidine may enhance the drowsiness caused by sedative drugs and alcohol … Concomitant use of Fedac with sympathomimetic agents or with MAOIs may cause a rise in blood pressure. Pseudoephedrine may reverse the hypotensive activity of drugs which interfere with sympathetic activity … Drowsiness, dryness of mouth, nervousness, restlessness, trouble in sleeping … There are no specific data on the use of triprolidine and pseudoephedrine during pregnancy … Not to be used in children less than 2 years of age","accessed":"2026-08-27"},{"id":"healthhub_trip","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/triprolidine","label":"HealthHub (MOH Singapore) — Triprolidine medication page (updated 3 Jun 2026; brand names incl. Fedac, Actifed, Decondine)","quote":"Relief of runny nose due to allergies, cold or flu … Relief of sneezing due to allergies … You may take this medication with or without food … Diabetes … Increased eye pressure (glaucoma) … Difficulty urinating or have a history of other bladder conditions … High blood pressure … Heart or thyroid disease … Do not take with or within 14 days of stopping monoamine oxidase inhibitors (MAOIs) such as moclobemide or selegiline … Avoid alcoholic drinks as this may increase drowsiness … Avoid driving or taking part in activities that require concentration while on this medication","accessed":"2026-08-27"},{"id":"healthhub_pse","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/loratadine-and-pseudoephedrine","label":"HealthHub (MOH Singapore) — Loratadine/Pseudoephedrine page, pseudoephedrine section (reviewed 26 Mar 2026)","quote":"Pseudoephedrine helps to relieve blocked nose … You may take this medication with or without food … High blood pressure … Heart disease or abnormal heart rhythm … Hyperthyroidism (overactive thyroid gland) … Diabetes … Glaucoma (high eye pressure) … Prostate or bladder problems … Trouble sleeping … Avoid taking too close to your sleep time … Restlessness … Do not take this medication with, or within 14 days of stopping, monoamine oxidase inhibitors","accessed":"2026-08-27"},{"id":"nhs_pse_who","url":"https://www.nhs.uk/medicines/pseudoephedrine/who-can-and-cannot-take-pseudoephedrine/","label":"NHS — Who can and cannot take pseudoephedrine (reviewed 2 Nov 2022)","quote":"high blood pressure (hypertension) … heart disease … taken medicines for depression known as monoamine oxidase inhibitors (MAOIs) in the last 2 weeks … diabetes … an overactive thyroid gland (hyperthyroidism) … glaucoma (increased pressure in the eye) … an enlarged prostate … liver or kidney problems","accessed":"2026-08-27"},{"id":"nhs_pse_interact","url":"https://www.nhs.uk/medicines/pseudoephedrine/taking-pseudoephedrine-with-other-medicines-and-herbal-supplements/","label":"NHS — Taking pseudoephedrine with other medicines and herbal supplements (reviewed 2 Nov 2022)","quote":"antidepressants known as monoamine oxidase inhibitors (MAOIs) … digoxin, a medicine for heart failure … tricyclic antidepressants, such as amitriptyline … ergot alkaloids, such as ergotamine (for migraine) … medicines for high blood pressure, such as beta blockers or methyldopa … other medicines for a blocked nose, such as xylometazoline and oxymetazoline","accessed":"2026-08-27"},{"id":"nhs_pse_how","url":"https://www.nhs.uk/medicines/pseudoephedrine/how-and-when-to-take-pseudoephedrine/","label":"NHS — How and when to take pseudoephedrine (reviewed 2 Nov 2022)","quote":"You can take pseudoephedrine tablets and liquid with or without food … You can take pseudoephedrine for a few days, usually up to 5 to 7 days, for the short-term relief of a stuffy or blocked nose … Taking too much pseudoephedrine can be dangerous. It can make you restless, make your heartbeat faster, and make you feel sick or vomit","accessed":"2026-08-27"},{"id":"hsa_adr_pse","url":"https://www.hsa.gov.sg/docs/default-source/announcements/adverse-drug-reaction-news-bulletin/adr_news_april2024_vol26_no1_amended.pdf?sfvrsn=118c6d24_3","label":"HSA Adverse Drug Reaction News Bulletin, Apr 2024 Vol 26 No 1 — pseudoephedrine and rare PRES/RCVS","quote":"A very small number of overseas cases of posterior reversible encephalopathy syndrome (PRES) and reversible cerebral vasoconstriction syndrome (RCVS) have been reported with pseudoephedrine … contraindicated the use of pseudoephedrine in patients with severe or uncontrolled hypertension or severe renal disease, which are risk factors for PRES and RCVS … there are 31 products currently registered. Of these, one is a Prescription Only Medicine while the others are Pharmacy Only Medicines … To date, HSA has not received any local adverse event report of PRES or RCVS associated with pseudoephedrine","accessed":"2026-08-27"},{"id":"hsa_reclass","url":"https://www.hsa.gov.sg/therapeutic-products/registration-of-therapeutic-products/variation-application/reclassification/list-of-reclassified-medicines/","label":"HSA — List of reclassified medicines (forensic class definitions: POM / P / GSL)","quote":"P: A therapeutic product that can be obtained from a pharmacist at a retail pharmacy without a prescription … GSL: A therapeutic product that can be obtained from any retailer","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:19.87501+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}