{"ok":true,"entry":{"slug":"erythromycin","kind":"medication","name":"erythromycin","aliases":["Erythrocin"],"brands_sg":["Eryson","Erycyn","Ermycin","Retorin","Erysol"],"class":"macrolide antibiotic","tags":["antibiotic"],"use_for":"bacterial infections: chest, dental, sti, skin (nhs)","use_after":"nhs: usually 2 to 4 times a day, doses spaced evenly","use_duration":null,"take_with":"water · nhs: the packet says if before or with food","pros":["nhs: most adults and children can take it","sg: registered as tablets and as an oral suspension","nhs: courses usually run a few days or weeks"],"cons":["nausea, vomiting, diarrhoea and bloating are common","sg label: not with domperidone, pimozide or cisapride","nhs: liver or gallbladder problems are a rare risk"],"dose_note":"the singapore erycyn-250 label sets the everyday figure as ‘250 mg 6 hrly; the dose may be doubled for severe infections’, and its highest quoted regimen is ‘1gm 6hrly for 10–15 days’ for syphilis — 4 g a day. the us erythromycin tablet label states the ceiling plainly: ‘dosage may be increased up to 4 g per day according to the severity of the infection’, and for children ‘this dosage may be doubled but should not exceed 4 g per day’. nhs gives no mg figure at all, only ‘2 to 4 times a day for a few days or weeks’. as directed on the label or by your doctor.","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["liver or kidney problems — nhs says tell your doctor first","myasthenia gravis or porphyria — nhs: it may not suit","sg label: a history of qt prolongation or arrhythmia","sg label: low potassium or magnesium (electrolyte disturbance)"],"clashes":[{"src":["ndf_erycyn","nhs_ery_mix"],"note":"sg label lists these as contraindicated; nhs names domperidone and pimozide among medicines that may not mix well","with":"domperidone, cisapride, pimozide, terfenadine, astemizole"},{"src":["nhs_ery_mix"],"note":"nhs lists anticoagulants among medicines that may not mix well with erythromycin","with":"warfarin, rivaroxaban and other anticoagulants"},{"src":["nhs_ery_mix"],"note":"nhs lists statin medicines among those that may not mix well with erythromycin","with":"statins such as simvastatin and lovastatin"},{"src":["nhs_ery_mix"],"note":"nhs: the herbal supplement is not to be used while taking erythromycin","with":"st john's wort"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached in full and filtered locally)","quote":"All 6 registered erythromycin products read 'Prescription Only' — SIN00578P ERYSON TABLETS 250 mg · SIN11952P ERYCYN-250 · SIN07545P ERMYCIN 250 · SIN11245P RETORIN · SIN00126P ERYSOL · SIN10446P ERYSON LOTION 2%","accessed":"2026-08-27"},{"id":"nhs_ery_about","url":"https://www.nhs.uk/medicines/erythromycin/","label":"NHS Medicines A-Z — Erythromycin: what it is for","quote":"Erythromycin is mainly used to treat bacterial infections, including: chest infections, dental abscesses, sexually transmitted infections (STIs). It's also sometimes used to treat skin conditions such as acne and rosacea.","accessed":"2026-08-27"},{"id":"nhs_ery_dose","url":"https://www.nhs.uk/medicines/erythromycin/","label":"NHS Medicines A-Z — Erythromycin: how to take it","quote":"Most people need to take it 2 to 4 times a day for a few days or weeks … check the packet or leaflet to see if you need to take it before, or with, food","accessed":"2026-08-27"},{"id":"nhs_ery_se","url":"https://www.nhs.uk/medicines/erythromycin/","label":"NHS Medicines A-Z — Side effects of erythromycin","quote":"Common side effects of erythromycin include: feeling sick (nausea) and being sick (vomiting), diarrhoea, not wanting to eat as much (loss of appetite), bloating and indigestion","accessed":"2026-08-27"},{"id":"nhs_ery_who","url":"https://www.nhs.uk/medicines/erythromycin/","label":"NHS Medicines A-Z — Who can and cannot take erythromycin","quote":"Most adults and children can take erythromycin … it may not be suitable if: you've had an allergic reaction … you have liver or kidney problems, you have myasthenia gravis, you have a blood condition called porphyria","accessed":"2026-08-27"},{"id":"nhs_ery_mix","url":"https://www.nhs.uk/medicines/erythromycin/","label":"NHS Medicines A-Z — Taking erythromycin with other medicines, food and drink","quote":"domperidone … anticoagulants like warfarin or rivaroxaban … pimozide or amisulpride … statin medicines, such as simvastatin and lovastatin. Do not use the herbal supplement St John's wort when taking erythromycin.","accessed":"2026-08-27"},{"id":"ndf_erycyn","url":"https://www.ndf.gov.sg/about-drugs/product-information/SIN11952P","label":"National Drug Formulary (SG, MOH) — ERYCYN-250 TABLET 250 mg [SIN11952P]: dosage and contraindications","quote":"DOSAGE AND ADMINISTRATION: 250 mg 6 hrly; the dose may be doubled for severe infections … Syphilis: 1gm 6hrly for 10–15 days … contraindicated in patients taking astemizole, terfenadine, domperidone, cisapride or pimozide","accessed":"2026-08-27"},{"id":"fda_erythromycin","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22ERYTHROMYCIN%22+AND+openfda.route:%22ORAL%22&limit=3","label":"US FDA label — erythromycin tablets (Zydus), DOSAGE AND ADMINISTRATION, via openFDA","quote":"The usual dosage of Erythromycin Tablets is one 250 mg tablet four times daily … Dosage may be increased up to 4 g per day according to the severity of the infection … should not exceed 4 g per day","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:18.585742+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}