{"ok":true,"entry":{"slug":"dicyclomine","kind":"medication","name":"dicyclomine","aliases":["dicycloverine","Bentyl"],"brands_sg":["Veragel-DMS","Colimix"],"class":"antispasmodic","tags":["digestive"],"use_for":"gut spasm and cramping pain, including in ibs","use_after":"sg veragel label: 1 hour after meals and at bedtime","use_duration":null,"take_with":"water · sg colimix syrup is measured, not spooned","pros":["fda: an antispasmodic and antimuscarinic for ibs","sg labels: both products are pharmacy-only, not rx","sg colimix label: also used for wind and trapped gas"],"cons":["fda: dizziness, dry mouth, blurred vision, drowsiness","fda: contraindicated in glaucoma and myasthenia gravis","fda: contraindicated if breastfeeding or under 6 months"],"dose_note":"no single-ingredient dicyclomine product is registered in singapore; both sg products are combinations and their national drug formulary inserts read “1 to 2 tablets four times a day, to be taken 1 hour after meals and at bedtime” (veragel-dms, 2.5 mg dicyclomine per tablet) and, for colimix syrup (5 mg/5 ml), “adults: 10 ml 3 to 4 times daily and at bedtime … do not exceed the stated dose”. the us fda dicyclomine label puts the single-ingredient ceiling higher: “starting dose: 20 mg four times a day … the dose may be escalated to 40 mg four times a day”, adding that “documented safety data are not available for doses above 80 mg daily for periods longer than 2 weeks”. as directed on the label or by your pharmacist or doctor.","dosage":null,"ul_status":null,"sg_class":"pharmacy-only","cautions":["glaucoma, obstructive uropathy or gut obstruction — fda: contraindicated","myasthenia gravis or severe ulcerative colitis — fda: contraindicated","breastfeeding — fda: contraindicated; excreted in human milk","impaired liver or kidney function — fda: caution must be taken"],"clashes":[{"src":["fda_dicy_di"],"note":"fda: anticholinergics antagonise antiglaucoma agents and may increase intraocular pressure","with":"antiglaucoma agents"},{"src":["fda_dicy_di"],"note":"fda: may increase certain actions or side effects of anticholinergic drugs","with":"antihistamines, tricyclics, antipsychotics, benzodiazepines"},{"src":["fda_dicy_di"],"note":"fda: may antagonise the effects of drugs that alter gastrointestinal motility","with":"metoclopramide and other gut-motility drugs"},{"src":["fda_dicy_di"],"note":"fda: antacids interfere with the absorption of anticholinergic agents","with":"antacids"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached locally at /tmp/hsa_all.json and filtered locally, not re-fetched)","quote":"Both registered dicyclomine products carry Forensicclassification 'Pharmacy Only' — SIN02547P VERAGEL-DMS TABLET (aluminium hydroxide-magnesium carbonate 325 mg && dicyclomine HCl 2.5 mg && dimethicone 10 mg) · SIN03333P COLIMIX SYRUP (dicyclomine HCl 5 mg/5 ml && simethicone 50 mg/5 ml)","accessed":"2026-08-27"},{"id":"ndf_veragel_ind","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin02547p/","label":"Singapore National Drug Formulary — VERAGEL-DMS TABLET [SIN02547P], Product Info and Indication","quote":"Forensic Classification PHARMACY ONLY MEDICINES … Indications: For the management and treatment of hyperacidity, gastritis and peptic ulcer.","accessed":"2026-08-27"},{"id":"ndf_veragel_dose","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin02547p/","label":"Singapore National Drug Formulary — VERAGEL-DMS TABLET [SIN02547P], Dosage/Times of administration","quote":"1 to 2 tablets four times a day, to be taken 1 hour after meals and at bedtime or, as recommended by a doctor.","accessed":"2026-08-27"},{"id":"ndf_colimix_ind","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin03333p/","label":"Singapore National Drug Formulary — COLIMIX SYRUP [SIN03333P], Indication and Contraindication","quote":"In older children and adults, Colimix is equally effective in relieving flatulence (wind) and abdominal discomfort due to entrapped gas … Dicyclomine is not recommended for use in infants under the age of six months.","accessed":"2026-08-27"},{"id":"ndf_colimix_dose","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin03333p/","label":"Singapore National Drug Formulary — COLIMIX SYRUP [SIN03333P], Dosage","quote":"Adults: 10 ml 3 to 4 times daily and at bedtime … Children 4 to 12 years: 5 to 10 ml 4 times daily … Do not exceed the stated dose.","accessed":"2026-08-27"},{"id":"fda_dicy_ind","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22DICYCLOMINE+HYDROCHLORIDE%22+AND+_exists_:dosage_and_administration&limit=1","label":"US FDA label for dicyclomine hydrochloride capsules USP, Indications and Usage, via openFDA drug/label.json (effective 2023-07-24)","quote":"Dicyclomine hydrochloride capsules, USP are an antispasmodic and anticholinergic (antimuscarinic) agent indicated for the treatment of functional bowel/irritable bowel syndrome","accessed":"2026-08-27"},{"id":"fda_dicy_dose","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22DICYCLOMINE+HYDROCHLORIDE%22+AND+_exists_:dosage_and_administration&limit=1","label":"US FDA label for dicyclomine hydrochloride capsules USP, Dosage and Administration, via openFDA","quote":"Starting dose: 20 mg four times a day … the dose may be escalated to 40 mg four times a day … Documented safety data are not available for doses above 80 mg daily for periods longer than 2 weeks.","accessed":"2026-08-27"},{"id":"fda_dicy_ci","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22DICYCLOMINE+HYDROCHLORIDE%22+AND+_exists_:dosage_and_administration&limit=1","label":"US FDA label for dicyclomine hydrochloride capsules USP, Contraindications, via openFDA","quote":"Dicyclomine hydrochloride is contraindicated in infants less than 6 months of age … nursing mothers … and in patients with: … myasthenia gravis … glaucoma … obstructive uropathy … obstructive disease of the gastrointestinal tract … severe ulcerative colitis","accessed":"2026-08-27"},{"id":"fda_dicy_ar","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22DICYCLOMINE+HYDROCHLORIDE%22+AND+_exists_:dosage_and_administration&limit=1","label":"US FDA label for dicyclomine hydrochloride capsules USP, Adverse Reactions, via openFDA","quote":"The most serious adverse reactions include cardiovascular and central nervous system symptoms. The most common adverse reactions (> 5% of patients) are dizziness, dry mouth, vision blurred, nausea, somnolence, asthenia and nervousness","accessed":"2026-08-27"},{"id":"fda_dicy_di","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22DICYCLOMINE+HYDROCHLORIDE%22+AND+_exists_:dosage_and_administration&limit=1","label":"US FDA label for dicyclomine hydrochloride capsules USP, Drug Interactions, via openFDA","quote":"Antiglaucoma agents: anticholinergics antagonize antiglaucoma agents and may increase intraoccular pressure … Antacids: interfere with the absorption of anticholinergic agents … may antagonize the effects of drugs that alter gastrointestinal motility, such as metoclopramide","accessed":"2026-08-27"},{"id":"fda_dicy_pop","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22DICYCLOMINE+HYDROCHLORIDE%22+AND+_exists_:dosage_and_administration&limit=1","label":"US FDA label for dicyclomine hydrochloride capsules USP, Use in Specific Populations, via openFDA","quote":"Pregnancy: use only if clearly needed … Pediatric Use: Safety and effectiveness not established … Hepatic and renal impairment: caution must be taken with patients with significantly impaired hepatic and renal function … Dicyclomine hydrochloride is excreted in human milk.","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:18.585742+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}