{"ok":true,"entry":{"slug":"dextromethorphan","kind":"medication","name":"dextromethorphan","aliases":["DXM","Robitussin DM","Romilar"],"brands_sg":["Robitussin DM","Duro-Tuss DM","Beathorphan","Dexcophan","Strepsils Cough"],"class":"antitussive","tags":["cold-flu","respiratory"],"use_for":"dry, persistent cough — dulls the urge to cough","use_after":"every 6–8 hours when needed · sg label caps 4 doses a day","use_duration":null,"take_with":"with or without food · sipped slowly, undiluted (sg label)","pros":["pharmacy-only in sg — a pharmacist is involved","sg label sets a ceiling: max 4 doses per day","healthhub: may be taken with or without food"],"cons":["cochrane: no good evidence for or against otc cough","more adverse effects reported with dextromethorphan","drowsiness or dizziness — driving care advised"],"dose_note":"sg label for duro-tuss dm dry cough liquid 15 mg/5 ml (pharmacy only, SIN17494P) reads 'Adults & Children over 12 years old — 10mL — Every 6 to 8 hours (Maximum 4 doses per day)'; healthhub adds that if symptoms do not go away or worsen after one week, speak to your healthcare professional; strengths differ a lot between sg products (5 mg lozenge to 30 mg tablet), so the per-product label is the one that counts — as directed on the label or by your pharmacist","dosage":null,"ul_status":null,"sg_class":"pharmacy-only","cautions":["maoi antidepressant now or in the last 14 days — sg label says do not take","ssri or snri antidepressants — healthhub says tell your healthcare professional","asthma or lung disease, or recently quit smoking — healthhub says say so first","cough past 3–4 weeks, fever over 38.6 °C — healthhub lists these as see-a-doctor signs"],"clashes":[{"src":["ndf_durotuss_dm","healthhub_dxm"],"note":"sg label: do not take if taking a prescription maoi, or if taken in the last 14 days","with":"monoamine oxidase inhibitors (moclobemide, selegiline, rasagiline)"},{"src":["healthhub_dxm"],"note":"healthhub asks that you tell your healthcare professional before use","with":"ssri / snri antidepressants (fluoxetine, sertraline, duloxetine, venlafaxine)"},{"src":["hsa_register","ndf_robitussin_dm"],"note":"sg register lists dextromethorphan combined with pseudoephedrine, promethazine, guaiphenesin or ephedrine — doubling up is easy to do by accident","with":"other cough and cold combinations containing dextromethorphan"}],"sources":[{"id":"healthhub_dxm","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/dextromethorphan","label":"HealthHub (MOH Singapore) — Dextromethorphan, uses / administration / side effects / interactions (article last reviewed 9 Jul 2026)","quote":"Dextromethorphan is a cough suppressant that works by reducing the urge to cough … may be taken with or without food … Drowsiness or dizziness … monoamine oxidase inhibitors (MAOIs) … selective serotonin reuptake inhibitors (SSRIs) … serotonin norepinephrine reuptake inhibitors (SNRIs)","accessed":"2026-08-27"},{"id":"healthhub_dxm_precautions","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/dextromethorphan","label":"HealthHub (MOH Singapore) — Dextromethorphan, precautions and warning-signs sections (article last reviewed 9 Jul 2026)","quote":"You have a history of asthma or lung diseases … you are a smoker or have recently taken steps to quit smoking … Fever more than 38.6 oC … Cough lasting for longer than three to four weeks","accessed":"2026-08-27"},{"id":"ndf_durotuss_dm","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin17494p/","label":"MOH National Drug Formulary — DURO-TUSS DM Dry Cough Liquid 15MG/5ML [SIN17494P] (HSA-registered product record, indication and contraindications)","quote":"Forensic Classification: PHARMACY ONLY MEDICINES … DURO-TUSS DM Dry Cough Liquid is used to relieve persistent dry cough for adults and children … Do not take this medicine if … you are currently taking a prescription monoamine oxidase inhibitor (MAOI)","accessed":"2026-08-27"},{"id":"ndf_durotuss_dm_dose","url":"https://isomer-user-content.by.gov.sg/544/634a8dbb-b063-497c-9743-fdae97195507/DuroTuss-Table1.png","label":"MOH National Drug Formulary — DURO-TUSS DM Dry Cough Liquid [SIN17494P], dosing table (the table is published as an image on the NDF product page)","quote":"Shake the bottle before use … Adults & Children over 12 years old — 10mL — Every 6 to 8 hours (Maximum 4 doses per day) … For oral use only. If cough persists, see your doctor or pharmacist.","accessed":"2026-08-27"},{"id":"ndf_robitussin_dm","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin12222p/","label":"MOH National Drug Formulary — ROBITUSSIN DM SYRUP [SIN12222P] (HSA-registered product record)","quote":"ROBITUSSIN DM SYRUP [SIN12222P] … DEXTROMETHORPHAN HBR - 30 MG/10 ML … GUAIPHENESIN - 200 MG/10 ML … Forensic Classification: PHARMACY ONLY MEDICINES … Licence Holder: HALEON SINGAPORE PTE. LTD.","accessed":"2026-08-27"},{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA register of therapeutic products (data.gov.sg open data d_767279312753558cbf19d48344577084, datastore_search API) — dextromethorphan rows","quote":"Productname: BEATHORPHAN TABLETS 15 mg … Activeingredients: DEXTROMETHORPHAN HBr … Forensicclassification: Pharmacy Only … Productname: Strepsils Cough for Dry Cough Lozenges 5mg … Forensicclassification: Pharmacy Only","accessed":"2026-08-27"},{"id":"cochrane2014","url":"https://europepmc.org/article/PMC/PMC7061814","label":"Cochrane Database of Systematic Reviews — Over-the-counter (OTC) medications for acute cough in children and adults in community settings (Smith, Schroeder, Fahey 2014; PMC7061814)","quote":"There is no good evidence for or against the effectiveness of OTC medicines in acute cough … higher numbers of adverse effects in participants taking preparations containing antihistamines and dextromethorphan … antitussives … were no more effective than placebo","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:18.585742+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}