{"ok":true,"entry":{"slug":"dapagliflozin","kind":"medication","name":"dapagliflozin","aliases":["Forxiga"],"brands_sg":["Forxiga","Edistride","Dapagliflozin Sandoz","Dafasglit","Dapiga"],"class":"SGLT2 inhibitor","tags":["diabetes"],"use_for":"type 2 diabetes, heart failure and chronic kidney disease","use_after":"sg label: once daily, any time of day, regardless of meals","use_duration":null,"take_with":"with or without food · healthhub: extra water each day","pros":["sg label: 10 mg once daily across all three uses","label: no dose change based on kidney function","healthhub: also used in heart failure without diabetes"],"cons":["genital and urinary tract infections are common","dehydration and low blood pressure can occur","rare diabetic ketoacidosis is flagged on the label"],"dose_note":"the sg forxiga label repeats one dose for each of its three uses — type 2 diabetes, heart failure and chronic kidney disease — \"The recommended dose of FORXIGA is 10 mg taken orally once daily at any time of the day regardless of meals\", and gives no higher dose; 10 mg is also the largest single-ingredient strength registered in singapore — as directed on the label or by your doctor","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["type 1 diabetes — healthhub: this medication is not recommended for type 1 diabetes mellitus, and the sg label says it is not indicated for it","a past episode of diabetic ketoacidosis, frequent alcohol use, or long fasts — healthhub links these to the rare dka risk","a planned operation or procedure — healthhub notes the medicine may need to be stopped temporarily at least 72 hours before","foot ulcers or infections, or a history of urinary tract infections — healthhub asks that these be declared"],"clashes":[{"src":["nhs_dapagliflozin_int"],"note":"nhs lists them among medicines that may not mix well with dapagliflozin","with":"fluid tablets (diuretics) such as furosemide"},{"src":["nhs_dapagliflozin_int","hh_dapagliflozin_se"],"note":"nhs lists them; healthhub notes the chance of low blood sugar rises when combined","with":"other diabetes medicines such as gliclazide or insulin"},{"src":["nhs_dapagliflozin_int"],"note":"nhs lists them among medicines that may not mix well with dapagliflozin","with":"medicines that lower blood pressure"},{"src":["nhs_dapagliflozin_int"],"note":"nhs lists lithium among medicines that may not mix well with dapagliflozin","with":"lithium"},{"src":["hh_dapagliflozin_food","nhs_dapagliflozin_int"],"food":true,"note":"healthhub describes flushing, nausea, vomiting, headache and fast heartbeat; nhs adds that it can lower blood pressure","with":"alcohol"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/api/action/datastore_search?resource_id=d_767279312753558cbf19d48344577084&limit=6000","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg d_767279312753558cbf19d48344577084), Forensicclassification column; cached at /tmp/hsa_all.json and filtered locally, not re-fetched","quote":"FORXIGA TABLET 10mg SIN14542P | Dapagliflozin propanediol 12.30mg eqv dapagliflozin | Prescription Only | A10BK01; FORXIGA 5MG SIN14541P; EDISTRIDE 10MG SIN17048P; DAPAGLIFLOZIN SANDOZ 10MG SIN17199P; DAFASGLIT 10 SIN17469P; DAPIGA 10MG SIN17427P — all 12 dapagliflozin rows Prescription Only","accessed":"2026-08-27"},{"id":"ndf_forxiga","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin14542p/","label":"MOH National Drug Formulary (Singapore) — FORXIGA TABLET 10MG [SIN14542P], product information","quote":"DAPAGLIFLOZIN PROPANEDIOL 12.3 MG EQV DAPAGLIFLOZIN - 10 MG … Forensic Classification PRESCRIPTION ONLY MEDICINES … Anatomical Therapeutic Chemical (ATC) code A10BK01 … Prescription-only Medicines with Exemptions for Supply without Prescription NA","accessed":"2026-08-27"},{"id":"ndf_forxiga_ind","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin14542p/","label":"MOH National Drug Formulary (Singapore) — FORXIGA [SIN14542P], 4.1 Therapeutic indications","quote":"FORXIGA is indicated in adults with type 2 diabetes mellitus to improve glycemic control … in adults with heart failure (NYHA class II–IV) … in adults with chronic kidney disease at risk of progression","accessed":"2026-08-27"},{"id":"ndf_forxiga_t1d","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin14542p/","label":"MOH National Drug Formulary (Singapore) — FORXIGA [SIN14542P], 4.1 Therapeutic indications: type 1 diabetes","quote":"FORXIGA is not indicated for use in patients with type 1 diabetes. FORXIGA should not be used for the treatment of diabetic ketoacidosis.","accessed":"2026-08-27"},{"id":"ndf_forxiga_dose","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin14542p/","label":"MOH National Drug Formulary (Singapore) — FORXIGA [SIN14542P], 4.2 Posology and method of administration","quote":"Type 2 diabetes mellitus The recommended dose of FORXIGA is 10 mg taken orally once daily at any time of the day regardless of meals. Heart failure The recommended dose of FORXIGA is 10 mg","accessed":"2026-08-27"},{"id":"ndf_forxiga_renal","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin14542p/","label":"MOH National Drug Formulary (Singapore) — FORXIGA [SIN14542P], patients with renal impairment","quote":"No dosage adjustment is required based on renal function. Due to limited experience, it is not recommended to initiate treatment with FORXIGA in patients with GFR < 25 mL/min","accessed":"2026-08-27"},{"id":"hh_dapagliflozin","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/dapagliflozin","label":"HealthHub (MOH Singapore) — Dapagliflozin, medication information leaflet","quote":"Dapagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor … If you suffer from heart failure, this medication can also be given to you to help with your heart condition, even if you do not have diabetes.","accessed":"2026-08-27"},{"id":"hh_dapagliflozin_admin","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/dapagliflozin","label":"HealthHub (MOH Singapore) — Dapagliflozin, how to take it","quote":"Follow the instructions on your medication label and take the medication as prescribed by your doctor. It is usually taken once a day. You may take this medication before food or after food.","accessed":"2026-08-27"},{"id":"hh_dapagliflozin_prec","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/dapagliflozin","label":"HealthHub (MOH Singapore) — Dapagliflozin, precautions","quote":"Have Type 1 diabetes mellitus, as this medication is not recommended for Type 1 diabetes mellitus … Suffered from diabetic ketoacidosis in the past … Plan to go for any surgery or procedure","accessed":"2026-08-27"},{"id":"hh_dapagliflozin_prec2","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/dapagliflozin","label":"HealthHub (MOH Singapore) — Dapagliflozin, further precautions","quote":"Have any foot ulcers/ infections Drink alcohol often … Have a history of urinary tract infections … you may need to stop the medication temporarily at least 72 hours before that","accessed":"2026-08-27"},{"id":"hh_dapagliflozin_se","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/dapagliflozin","label":"HealthHub (MOH Singapore) — Dapagliflozin, common side effects","quote":"Genital infections … Urinary tract infection … Low blood pressure … Dehydration (not having enough water in the body) … You should take an extra 1 to 2 glasses of water every day … Low blood sugar","accessed":"2026-08-27"},{"id":"hh_dapagliflozin_dka","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/dapagliflozin","label":"HealthHub (MOH Singapore) — Dapagliflozin, rare but serious side effects","quote":"Diabetic ketoacidosis (DKA) DKA is a rare and serious side effect associated with this medication.","accessed":"2026-08-27"},{"id":"hh_dapagliflozin_food","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/dapagliflozin","label":"HealthHub (MOH Singapore) — Dapagliflozin, food and medication to avoid","quote":"Avoid taking alcohol with this medication as it may cause symptoms such as flushing, nausea, vomiting, headache, fast heartbeat, fast breathing and giddiness.","accessed":"2026-08-27"},{"id":"nhs_dapagliflozin_int","url":"https://www.nhs.uk/medicines/dapagliflozin/","label":"NHS medicines A–Z — Dapagliflozin, taking it with other medicines, food and drink (reviewed 26 June 2026)","quote":"These include: medicines to treat build-up of fluid (oedema) in the body, such as furosemide some other diabetes medicines, such as gliclazide medicines that can lower your blood pressure lithium","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:16.693643+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}