{"ok":true,"entry":{"slug":"clonazepam","kind":"medication","name":"clonazepam","aliases":["Rivotril"],"brands_sg":["Clonotril","Clonazepam Mevon"],"class":"benzodiazepine","tags":["mental-health"],"use_for":"prescribed for anxiety, panic, insomnia or seizures","use_after":"healthhub: with or without food, as the doctor directs","use_duration":null,"take_with":"water · healthhub: alcohol can cause excessive sleepiness","pros":["healthhub: for short-term anxiety or panic symptoms","healthhub: also used for some types of seizures","healthhub: most side effects improve with time"],"cons":["healthhub: habit-forming at high doses or long use","healthhub: drowsiness, dizziness, feeling unsteady","healthhub: abrupt stopping can trigger withdrawal fits"],"dose_note":"the us fda label for klonopin states, for seizure disorders in adults, 'The initial dose for adults with seizure disorders should not exceed 1.5 mg/day divided into three doses … Maximum recommended daily dose is 20 mg'. for panic disorder the same label sets a target of 1 mg/day and says 'it is possible that some individual patients may benefit from doses of up to a maximum dose of 4 mg/day', noting that 2, 3 and 4 mg/day 'were less effective than the 1 mg/day dose and were associated with more adverse effects'. only 0.5 mg tablets are registered in singapore. in singapore the prescriber sets the dose.","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["lung, brain, kidney or liver disease (healthhub)","past drug or alcohol misuse (healthhub)","glaucoma, seizures, myasthenia gravis or sleep apnoea (healthhub)","pregnancy, planning pregnancy or breastfeeding (healthhub)"],"clashes":[{"src":["hh_clo_avoid"],"food":true,"note":"healthhub: it can cause excessive sleepiness","with":"alcohol"},{"src":["nhs_clo_herbs"],"note":"nhs: they can increase the drowsy effects of clonazepam and may have other side effects","with":"valerian, passionflower and similar herbal sedatives"},{"src":["nhs_clo_mix"],"note":"nhs lists these among medicines that affect how clonazepam works or add side effects","with":"strong painkillers (codeine, methadone, morphine, oxycodone, tramadol)"},{"src":["nhs_clo_mix"],"note":"nhs lists these among medicines to tell a doctor about before starting clonazepam","with":"antipsychotics, antidepressants, hypnotics, sedating antihistamines"},{"src":["nhs_clo_mix"],"note":"nhs lists these among medicines that affect the way clonazepam works","with":"cimetidine, rifampicin, fluconazole, blood-pressure medicines"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached in full and filtered locally)","quote":"Both registered clonazepam products carry Forensicclassification 'Prescription Only' — SIN06410P CLONOTRIL 0.5 TABLET 0.5 mg · SIN17075P CLONAZEPAM MEVON TABLETS 0.5 MG. No product named RIVOTRIL appears in the dataset.","accessed":"2026-08-27"},{"id":"hh_clo_uses","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/clonazepam","label":"HealthHub (National Medication Information workgroup, SG) — Clonazepam: what is this medication for","quote":"Clonazepam is used for short term treatment of insomnia (difficulty sleeping), anxiety, panic symptoms or controlling certain types of seizures (fits).","accessed":"2026-08-27"},{"id":"hh_clo_howto","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/clonazepam","label":"HealthHub — Clonazepam: how should I take this medication","quote":"Follow the instructions on your medication label and take this medication as prescribed by your doctor. This medication may be taken with or without food … obtain this medication from the same doctor or clinic whenever possible.","accessed":"2026-08-27"},{"id":"hh_clo_side","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/clonazepam","label":"HealthHub — Clonazepam: common side effects","quote":"Nausea or stomach discomfort … Constipation … Dizziness … Drowsiness or feeling tired … Feeling clumsy or unsteady. Most of the side effects listed here will improve with time.","accessed":"2026-08-27"},{"id":"hh_clo_habit","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/clonazepam","label":"HealthHub — Clonazepam: dependence and habit-forming potential","quote":"This medication may be habit-forming when taken excessively or for a prolonged duration (especially at high doses) … On a short-term basis (2 - 4 weeks); At the lowest effective dose; Intermittently","accessed":"2026-08-27"},{"id":"hh_clo_withdrawal","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/clonazepam","label":"HealthHub — Clonazepam: stopping the medication","quote":"do not stop taking it abruptly as it may lead to withdrawal symptoms such as increased sweating, increased heart rate, tremors, trouble sleeping, increased agitation, hallucinations … and in severe cases, medical emergencies such as fits.","accessed":"2026-08-27"},{"id":"hh_clo_precautions","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/clonazepam","label":"HealthHub — Clonazepam: what precautions should I take","quote":"Lung, brain, kidney or liver disease; Previous drug or alcohol abuse; Glaucoma (high pressure in the eyes), seizures (fits), Myasthenia Gravis … or sleep apnea … You are pregnant, planning to become pregnant, or breastfeeding.","accessed":"2026-08-27"},{"id":"hh_clo_avoid","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/clonazepam","label":"HealthHub — Clonazepam: what food or medication should I avoid","quote":"Avoid drinking alcohol while taking Clonazepam as it can cause excessive sleepiness.","accessed":"2026-08-27"},{"id":"nhs_clo_mix","url":"https://www.nhs.uk/medicines/clonazepam/taking-clonazepam-with-other-medicines-and-herbal-supplements/","label":"NHS Medicines A-Z — Taking clonazepam with other medicines and herbal supplements","quote":"anticonvulsants … antipsychotics or antidepressants … hypnotics … medicines used to lower blood pressure … drowsy (sedating) antihistamines … strong painkillers such as codeine, methadone, morphine, oxycodone, pethidine or tramadol; cimetidine … rifampicin … fluconazole","accessed":"2026-08-27"},{"id":"nhs_clo_herbs","url":"https://www.nhs.uk/medicines/clonazepam/taking-clonazepam-with-other-medicines-and-herbal-supplements/","label":"NHS Medicines A-Z — Mixing clonazepam with herbal remedies or supplements","quote":"Do not take herbal remedies for anxiety or insomnia, such as valerian or passionflower, with clonazepam. They can increase the drowsy effects of clonazepam and may also have other side effects.","accessed":"2026-08-27"},{"id":"fda_klonopin_seizure","url":"https://api.fda.gov/drug/label.json?search=openfda.brand_name:%22KLONOPIN%22&limit=1","label":"US FDA label for KLONOPIN (clonazepam), Dosage and Administration — Seizure Disorders, Adults, via openFDA (effective 2025-12-01)","quote":"The initial dose for adults with seizure disorders should not exceed 1.5 mg/day divided into three doses … Maintenance dosage must be individualized for each patient depending upon response. Maximum recommended daily dose is 20 mg.","accessed":"2026-08-27"},{"id":"fda_klonopin_panic","url":"https://api.fda.gov/drug/label.json?search=openfda.brand_name:%22KLONOPIN%22&limit=1","label":"US FDA label for KLONOPIN (clonazepam), Dosage and Administration — Panic Disorder, Adults, via openFDA","quote":"Higher doses of 2, 3 and 4 mg/day in that study were less effective than the 1 mg/day dose … it is possible that some individual patients may benefit from doses of up to a maximum dose of 4 mg/day","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:16.693643+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}