{"ok":true,"entry":{"slug":"chanca-piedra","kind":"supplement","name":"chanca piedra","aliases":["Phyllanthus niruri","stonebreaker"],"brands_sg":["Swanson Vitamins","Nutricost","Whole World Botanicals","Advanced Orthomolecular Research AOR","NutraMedix"],"class":"botanical","tags":["general"],"use_for":"studied around kidney stones — results are mixed","use_after":null,"use_duration":null,"take_with":null,"pros":["the review found no significant adverse effects","widely used in traditional medicine"],"cons":["results across studies are mixed","dosage questions remain unanswered in reviews","evidence is as an add-on to procedures, not alone"],"dose_note":"no standard dose is established; reviews say specific dosages, treatment duration and interactions remain unanswered","dosage":{"ul":null,"unit":null,"fda_dv":null,"rda_ai":null,"ul_status":"none_established","population":"general adult","hsa_max_daily":null},"ul_status":"none_established","sg_class":null,"cautions":["not a replacement for stone treatment — studied as an add-on","singapore: not listed in HSA annex A/B — that is not the same as cleared"],"clashes":[],"sources":[{"id":"epmc_pn_sr2025","url":"https://europepmc.org/article/MED/40480426","label":"Phyllanthus niruri in the management of nephrolithiasis: a systematic review of the literature (Actas Urol Esp, 2025)","quote":"Phyllanthus niruri (PN), widely used in traditional medicine, has been extensively researched, yielding mixed results … Growing evidence suggests that PN, when used alongside traditional interventions, is safe, without significant adverse effects, and may improve SFR outcomes after ESWL.","accessed":"2026-08-27"},{"id":"epmc_urolithiasis2025","url":"https://europepmc.org/article/PMC/PMC12072574","label":"Phytotherapy in urolithiasis: an updated overview of current knowledge (J Clin Med, 2025)","quote":"While research on phytotherapy is still limited, it is ongoing and is yielding promising results … several questions regarding specific dosages, mechanisms of action, drug interactions, treatment duration, and types of stones that respond to phytotherapy remain unanswered.","accessed":"2026-08-27"},{"id":"hsa_prohibited","url":"https://file.go.gov.sg/hsa-chp-prohibited-restricted-ing-guidelines.pdf","label":"HSA — Guidelines on prohibited and restricted ingredients in health supplements and traditional medicines (Oct 2025), Annex A/B","quote":"The objective of this guideline is to highlight the substances of concern when used in HS and TM and is not meant to be an exhaustive list.","accessed":"2026-08-27"},{"id":"iherb_sg","url":"https://sg.iherb.com/c/chanca-piedra","label":"iHerb Singapore — Chanca Piedra category page (default best-selling order)","quote":"Chanca Piedra","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:14.713299+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}