{"ok":true,"entry":{"slug":"cephalexin","kind":"medication","name":"cephalexin","aliases":["cefalexin","Keflex","Ospexin"],"brands_sg":["Felexin","Cefalexin","Apo-Cephalex","Sofilex","Axcel Cephalexin"],"class":"first-generation cephalosporin","tags":["antibiotic"],"use_for":"prescribed for lung, urine and skin infections","use_after":"doses spaced evenly · often 500 mg 2 or 3 times a day","use_duration":null,"take_with":"water · with or without food; food may ease nausea","pros":["most people feel better within a few days (nhs)","food optional — with or without a meal (nhs)","alcohol allowed per nhs"],"cons":["nausea and diarrhoea are the most common effects","nhs advises against zinc supplements alongside it","penicillin allergy history needs a check first"],"dose_note":"nhs: for most infections adults usually take 500 mg, 2 or 3 times a day. us label: \"up to 4 grams daily in two to four equally divided doses\" for more severe infections, and at creatinine clearance 30–59 ml/min the \"maximum daily dose should not exceed 1 g\". as directed on the label or by your pharmacist/doctor.","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["known hypersensitivity to cephalexin — us label contraindication","allergy to penicillins such as amoxicillin — healthhub says tell your professional","kidney problems — the us label caps the daily dose from 59 ml/min downwards","pregnant, planning pregnancy or breastfeeding — healthhub says tell your professional"],"clashes":[{"src":["nhs_cef_about"],"note":"nhs advises against taking zinc supplements while on cefalexin","with":"zinc supplements"},{"src":["fda_cephalexin"],"note":"us label: metformin concentrations rise; monitoring and metformin dose adjustment advised","with":"metformin"},{"src":["fda_cephalexin"],"note":"renal excretion of cephalexin is inhibited; the us label does not recommend the combination","with":"probenecid"},{"src":["hh_cephalexin"],"note":"sg leaflet lists warfarin among the things to declare before starting","with":"warfarin"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (official open dataset on data.gov.sg; full 5,511-row register pulled via the datastore_search API)","quote":"Forensicclassification = \"Prescription Only\" for all 12 cephalexin/cefalexin products on the register, all oral — e.g. SIN00449P FELEXIN 500 CAPSULE, SIN11396P CEFALEXIN CAPSULE 500 mg, SIN08381P APO-CEPHALEX TABLET, SIN10378P SOFILEX CAPSULE, SIN16585P AXCEL CEPHALEXIN-500.","accessed":"2026-08-27"},{"id":"nhs_cef_about","url":"https://www.nhs.uk/medicines/cefalexin/about-cefalexin/","label":"NHS Medicines A–Z — About cefalexin (brand name: Keflex)","quote":"Cefalexin is an antibiotic … only available on prescription … You'll usually start to feel better in a few days … Do not take zinc supplements while you're taking cefalexin … You can drink alcohol while taking cefalexin.","accessed":"2026-08-27"},{"id":"nhs_cef_how","url":"https://www.nhs.uk/medicines/cefalexin/how-and-when-to-take-cefalexin/","label":"NHS Medicines A–Z — How and when to take cefalexin","quote":"for most infections, adults usually take 500mg, 2 or 3 times a day … You can take cefalexin with or without food. Try to space the doses evenly throughout the day.","accessed":"2026-08-27"},{"id":"hh_cephalexin","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/cephalexin","label":"HealthHub (MOH Singapore / Pharmaceutical Society of Singapore) — Cephalexin medication information leaflet","quote":"Cephalexin is an antibiotic used to treat infections … of the lung, urine, skin … You may take this medication with or without food … You are allergic to penicillins, such as Amoxicillin … You are taking warfarin.","accessed":"2026-08-27"},{"id":"fda_cephalexin","url":"https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0384c418-b4d4-4c06-9ed9-13e864b1980b","label":"FDA DailyMed — Cephalexin capsules, USP (Bryant Ranch Prepack), SPL effective 16 Jul 2026; retrieved via the openFDA drug label API","quote":"up to 4 grams daily in two to four equally divided doses … maximum daily dose should not exceed 1 g … contraindicated … known hypersensitivity to cephalexin … increased metformin concentrations … renal excretion … inhibited by probenecid.","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:14.713299+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}