{"ok":true,"entry":{"slug":"carbocisteine","kind":"medication","name":"carbocisteine","aliases":["Rhinathiol","Mucosolvan alternative","carbocysteine"],"brands_sg":["Rhinathiol","Mucodin","Solmux","SCMC","Mucopront"],"class":"mucolytic","tags":["cold-flu"],"use_for":"chesty cough — thins and loosens mucus in the airways","use_after":"morning, midday and evening per the rhinathiol 5% label","use_duration":null,"take_with":"healthhub: with or without food · rhinathiol label: without","pros":["two rhinathiol syrups are general sale list","cochrane: one trial favoured mucolytics over placebo","healthhub: syrup, tablet or capsule forms in sg"],"cons":["cochrane: no good evidence for or against otc cough","nausea, vomiting, stomach pain and diarrhoea are common","rhinathiol 5% label: under 15 years — do not use"],"dose_note":"the singapore rhinathiol adults syrup 5% label [SIN02759P] reads 'one measuring cup in the morning, at midday and in the evening, without food and without exceeding 3 measuring cups per day' and 'one 15 ml measuring cup contains 750 mg of carbocisteine' — a stated ceiling of 3 cups, i.e. 2,250 mg a day, for adults over 15 only; the same label adds 'do not use this medicine in children under 15 years of age' and 'do not exceed 5 days of treatment without medical advice'; healthhub adds that if symptoms persist or worsen after one week, speak to your healthcare professional; as directed on the label or by your doctor or pharmacist","dosage":null,"ul_status":null,"sg_class":"pharmacy-only","cautions":["stomach or intestinal ulcer — the rhinathiol 5% label lists it as a contraindication","liver or kidney problems, copd or severe uncontrolled asthma — healthhub says say so first","cough with thick yellow or green phlegm or blood, fever above 38.6 °C, night sweats or weight loss — healthhub says say so first","pregnant, planning to be, or breastfeeding — healthhub says say so first"],"clashes":[{"src":["healthhub_carbo_precautions"],"note":"healthhub asks that you tell your healthcare professional what else you are taking; no specific interaction is named","with":"other medicines, supplements, traditional or herbal remedies"},{"src":["ndf_rhinathiol_warn"],"note":"the rhinathiol 5% label names it among the ingredients an allergy to which rules the product out","with":"methyl parahydroxybenzoate (a rhinathiol excipient)"}],"sources":[{"id":"healthhub_carbo","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/carbocisteine","label":"HealthHub (MOH Singapore) — Carbocisteine, uses / administration / side effects (article last reviewed 16 Dec 2025)","quote":"This medication is also known as carbocysteine. It is a mucolytic that works by thinning and loosening mucus in the airways … in the form of a syrup, tablet or capsule … taken with or without food","accessed":"2026-08-27"},{"id":"healthhub_carbo_precautions","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/carbocisteine","label":"HealthHub (MOH Singapore) — Carbocisteine, precautions and side-effect sections (article last reviewed 16 Dec 2025)","quote":"gastric ulcers, liver or kidney problems and lung conditions e.g. Chronic Obstructive Lung Disease (COPD) or severe uncontrolled asthma … Nausea Vomiting Stomach pain Diarrhoea … pregnant, planning to become pregnant or breastfeeding","accessed":"2026-08-27"},{"id":"ndf_rhinathiol","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin02759p/","label":"MOH National Drug Formulary — RHINATHIOL ADULTS SYRUP 5% [SIN02759P], Dosing section","quote":"one measuring cup in the morning, at midday and in the evening, without food and without exceeding 3 measuring cups per day … one 15 ml measuring cup contains 750 mg of carbocisteine","accessed":"2026-08-27"},{"id":"ndf_rhinathiol_warn","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin02759p/","label":"MOH National Drug Formulary — RHINATHIOL ADULTS SYRUP 5% [SIN02759P], age limit, duration and contraindications","quote":"Do not use this medicine in children under 15 years of age … Do not exceed 5 days of treatment without medical advice … if you have a stomach or intestinal ulcer … methyl parahydroxybenzoate","accessed":"2026-08-27"},{"id":"hsa_register_carbo","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA register of therapeutic products (data.gov.sg d_767279312753558cbf19d48344577084) — 7 carbocisteine / carbocysteine rows, filtered locally 27 Aug 26","quote":"RHINATHIOL ADULTS SYRUP 5% … General Sale List … RHINATHIOL 2% CHILDREN SYRUP … General Sale List … MUCODIN SYRUP 250 mg/5 ml … Pharmacy Only … SOLMUX PAEDIATRIC SUSPENSION … SCMC SYRUP 100 … Mucopront Capsule","accessed":"2026-08-27"},{"id":"cochrane2014","url":"https://europepmc.org/article/PMC/PMC7061814","label":"Cochrane Database of Systematic Reviews — OTC medications for acute cough in children and adults in community settings (Smith, Schroeder, Fahey 2014; PMC7061814)","quote":"The results of one trial favoured active treatment with mucolytics over placebo … There is no good evidence for or against the effectiveness of OTC medicines in acute cough","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:14.713299+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}