{"ok":true,"entry":{"slug":"burdock-root","kind":"supplement","name":"burdock root","aliases":["Arctium lappa","niu bang zi","gobo"],"brands_sg":["Nature's Answer","Swanson Vitamins","Frontier Co-op","Nature's Way","Nutricost"],"class":"botanical","tags":["skin-hair","general"],"use_for":"traditional skin use — human evidence is preliminary","use_after":null,"use_duration":null,"take_with":null,"pros":["long record in traditional chinese medicine","reviews map plausible anti-inflammatory pathways"],"cons":["limited human evidence — mostly cell and mouse work","no standardised dose; extracts vary batch to batch","pharmacokinetic and safety data remain insufficient"],"dose_note":"no standardised human dose; the 2025 review reports 10-100 uM in cell assays and 15-100 mg/kg in animal studies, not human amounts","dosage":{"ul":null,"unit":null,"fda_dv":null,"rda_ai":null,"ul_status":"none_established","population":"general adult","hsa_max_daily":null},"ul_status":"none_established","sg_class":null,"cautions":["pharmacokinetic and safety data are described as insufficient","singapore: not listed in HSA annex A/B — that is not the same as cleared"],"clashes":[],"sources":[{"id":"epmc_burdock_skin2025","url":"https://europepmc.org/article/PMC/PMC12531496","label":"Immunopharmacological potential of Arctium lappa L. in immune-mediated skin diseases: a critical review of experimental and clinical evidence (Front Pharmacol, 2025)","quote":"most data are derived from in vitro or murine models using heterogeneous preparations, with limited clinical validation … the evidence remains preliminary … a lack of standardized dosing, and the absence of robust randomized clinical trials.","accessed":"2026-08-27"},{"id":"epmc_burdock_root2024","url":"https://europepmc.org/article/PMC/PMC11335715","label":"Harnessing the power of Arctium lappa root: a review of its pharmacological properties and therapeutic applications (Nat Prod Bioprospect, 2024)","quote":"Arctium lappa, widely recognized as burdock, is a perennial plant that is employed in the realm of traditional Chinese medicine for a wide range of medicinal applications.","accessed":"2026-08-27"},{"id":"hsa_prohibited","url":"https://file.go.gov.sg/hsa-chp-prohibited-restricted-ing-guidelines.pdf","label":"HSA — Guidelines on prohibited and restricted ingredients in health supplements and traditional medicines (Oct 2025), Annex A/B","quote":"The objective of this guideline is to highlight the substances of concern when used in HS and TM and is not meant to be an exhaustive list.","accessed":"2026-08-27"},{"id":"iherb_sg","url":"https://sg.iherb.com/c/burdock-root","label":"iHerb Singapore — Burdock Root category page (default best-selling order)","quote":"Burdock Root","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:14.713299+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}