{"ok":true,"entry":{"slug":"boric-acid","kind":"supplement","name":"boric acid","aliases":["boric acid suppository"],"brands_sg":["Nutricost","AZO","pH-D Feminine Health","The Honey Pot Company","Vitamatic"],"class":"mineral compound","tags":["womens-health"],"use_for":"vaginal use in non-albicans or azole-resistant thrush","use_after":"after azole treatment fails","use_duration":"courses ran 14–21 days","take_with":null,"pros":["cdc: roughly 70% clinical and mycologic eradication","600 mg once daily per vagina is the best-supported dose","in 52 women with recurrent bv, 88.5% reached nugent <4"],"cons":["swallowing it is dangerous — 15,000–20,000 mg can kill","contraindicated in pregnancy — safety data are lacking","strengths and availability vary widely between products"],"dose_note":"the cdc regimen for non-albicans vulvovaginal candidiasis is 600 mg of boric acid in a gelatin capsule administered vaginally once daily for 3 weeks, with clinical and mycologic eradication rates of about 70%; a 2026 review states that most scientific and safety data support 600 mg daily per vagina, for 14–21 days, and that it is contraindicated in pregnancy — this is quoted guideline text, not an instruction","dosage":{"ul":20,"unit":"mg","fda_dv":null,"rda_ai":null,"ul_status":"established","population":"general adult, 19+ years — these figures are for ORAL BORON intake, not for a vaginal boric acid dose","hsa_max_daily":6.4},"ul_status":"established","sg_class":null,"cautions":["pregnancy — the 2026 review calls it contraindicated","accidental swallowing — vomiting, convulsions, vascular collapse","children and pets — the bv study counselled secure storage","hsa restricts boron: no more than 6.4 mg a day by mouth","in sg a supplement may not be promoted for fungal or infectious conditions"],"clashes":[{"src":["ods_boron_interactions"],"note":"ods: boron is not known to have any clinically relevant interactions with medications — that is not the same as none existing","with":"medicines generally"}],"sources":[{"id":"cdc_vvc","url":"https://www.cdc.gov/std/treatment-guidelines/candidiasis.htm","label":"CDC — STI Treatment Guidelines, Vulvovaginal Candidiasis (non-albicans VVC)","quote":"600 mg of boric acid in a gelatin capsule administered vaginally once daily for 3 weeks … This regimen has clinical and mycologic eradication rates of approximately 70%","accessed":"2026-08-27"},{"id":"vvc2026_dose","url":"https://europepmc.org/article/PMC/PMC13017020","label":"State-of-the-Art Review: Managing Vulvovaginal Candidiasis (Clin Infect Dis / Europe PMC 2026) — boric acid dose and pregnancy","quote":"boric acid is contraindicated in pregnancy because of a lack of safety data … most scientific and safety data supports the use of 600 mg of boric acid daily per vagina in a gelatine capsule.","accessed":"2026-08-27"},{"id":"vvc2026_table","url":"https://europepmc.org/article/PMC/PMC13017020","label":"Europe PMC 2026 VVC review — Table 2 treatment recommendations","quote":"Boric acid 600 mg p.v. for 14–21 days — For non-albicans Candida spp. and azole resistance. Not during pregnancy. Significant variation of availability, strengths and products","accessed":"2026-08-27"},{"id":"bv2025_results","url":"https://europepmc.org/article/PMC/PMC12584358","label":"Intravaginal boric acid treatment for recurrent bacterial vaginosis: short-term effects on vaginal health parameters (Europe PMC 2025) — results and limits","quote":"Nugent scores decreased from 7.8 ± 0.8 to 3.1 ± 1.0 (p < 0.001), with 88.5% achieving scores < 4 … the single-arm retrospective design and limited follow-up preclude definitive conclusions about treatment efficacy.","accessed":"2026-08-27"},{"id":"bv2025_counsel","url":"https://europepmc.org/article/PMC/PMC12584358","label":"Europe PMC 2025 boric acid BV study — safety counselling","quote":"the potential for serious toxicity if boric acid is ingested orally necessitates comprehensive patient education … the critical importance of keeping suppositories away from children and pets.","accessed":"2026-08-27"},{"id":"ods_boron_dris","url":"https://web.archive.org/web/20260816072918/https://ods.od.nih.gov/factsheets/Boron-HealthProfessional/","label":"NIH ODS — Boron, Fact Sheet for Health Professionals (Recommended Intakes) — read via the archive.org capture of 16 Aug 2026, since ods.od.nih.gov 403s to direct fetch","quote":"The FNB found the existing data insufficient to derive an RDA, AI, or EAR for boron. The World Health Organization estimates that an acceptable safe range of boron intakes for adults is 1–13 mg/day","accessed":"2026-08-27"},{"id":"ods_boron_ul","url":"https://web.archive.org/web/20260816072918/https://ods.od.nih.gov/factsheets/Boron-HealthProfessional/","label":"NIH ODS — Boron (Table 2: Tolerable Upper Intake Levels for Boron) — archive.org capture","quote":"The FNB established boron ULs for healthy individuals based on levels associated with reproductive and developmental effects in animals … 19+ years | 20 mg | 20 mg | 20 mg | 20 mg","accessed":"2026-08-27"},{"id":"ods_boron_dv","url":"https://web.archive.org/web/20260816072918/https://ods.od.nih.gov/factsheets/Boron-HealthProfessional/","label":"NIH ODS — Boron (no Daily Value) — archive.org capture","quote":"Because the FNB has not established an RDA or AI for boron, boron does not have a DV.","accessed":"2026-08-27"},{"id":"ods_boron_toxicity","url":"https://web.archive.org/web/20260816072918/https://ods.od.nih.gov/factsheets/Boron-HealthProfessional/","label":"NIH ODS — Boron (Health Risks from Excessive Boron) — archive.org capture","quote":"Symptoms associated with accidental consumption of boric acid or borax … include nausea, gastrointestinal discomfort, vomiting, diarrhea, skin flushing, rash, excitation, convulsions, depression, and vascular collapse … 15,000 to 20,000 mg can cause death in adults","accessed":"2026-08-27"},{"id":"ods_boron_interactions","url":"https://web.archive.org/web/20260816072918/https://ods.od.nih.gov/factsheets/Boron-HealthProfessional/","label":"NIH ODS — Boron (Interactions with Medications) — archive.org capture","quote":"Boron is not known to have any clinically relevant interactions with medications.","accessed":"2026-08-27"},{"id":"hsa_annexa_boron","url":"https://file.go.gov.sg/hsa-chp-prohibited-restricted-ing-guidelines.pdf","label":"HSA — Guidelines on Prohibited and Restricted Ingredients in HS and TM, GL-CHPB-1-012 Rev. No. 001 (Oct 2025), Annex A row 14","quote":"14. Boron — Restricted use in HS and TM — Maximum Daily Dose: When for oral use by general adult population, the maximum recommended daily dose should not provide more than 6.4mg","accessed":"2026-08-27"},{"id":"hsa_hs_table5","url":"https://file.go.gov.sg/hsa-hs-guidelines.pdf","label":"HSA — Health Supplements Guidelines (January 2026), Table 5: Minerals Limits","quote":"HS for use by the general adult population should not contain vitamins and minerals exceeding the stipulated limits stated in Tables 4 and 5 … Boron — 6.4 mg","accessed":"2026-08-27"},{"id":"hsa_table6","url":"https://file.go.gov.sg/hsa-hs-guidelines.pdf","label":"HSA — Health Supplements Guidelines (January 2026), Table 6: Examples of Diseases/Conditions/Disorders Not Allowed for Health Supplements","quote":"HS must not be labelled, advertised or promoted for any specific medicinal purpose … Skin, hair and nails — Fungal infection … Others — Cancers, infectious diseases, inflammatory conditions or diseases","accessed":"2026-08-27"},{"id":"iherb_sg","url":"https://sg.iherb.com/c/boric-acid","label":"iHerb Singapore — Boric Acid category (default order, 1 - 10 of 10 results); first 5 distinct brands in page order","quote":"Nutricost, Women, Boric Acid, Vaginal Suppository, 600 mg … AZO, Boric Acid, Vaginal Suppositories, 600 mg … pH-D Feminine Health, Boric Acid Vaginal Suppositories … The Honey Pot Company, Boric Acid & Herbs … Vitamatic, Boric Acid, 600 mg","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:12.75901+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}