{"ok":true,"entry":{"slug":"black-walnut","kind":"supplement","name":"black walnut","aliases":["Juglans nigra"],"brands_sg":["Nature's Answer","Swanson Vitamins","NOW Foods","Nature's Way","Kroeger Herb Co"],"class":"botanical","tags":["gut"],"use_for":"folk use for gut complaints; no human trials found","use_after":null,"use_duration":null,"take_with":null,"pros":["cell studies show cytokine suppression — not people","long folk history for gut complaints"],"cons":["no human trials — benefit in people is unknown","evidence is cell-culture only, not clinical","not on HSA's list — that is not proof of safety"],"dose_note":null,"dosage":{"ul":null,"unit":null,"fda_dv":null,"rda_ai":null,"ul_status":"none_established","population":"general adult","hsa_max_daily":null},"ul_status":"none_established","sg_class":null,"cautions":["tree-nut allergy — kernels are eaten as a food source","HSA does not list it, and that list is not exhaustive"],"clashes":[],"sources":[{"id":"ho2019","url":"https://europepmc.org/article/PMC/PMC6761373","label":"Black Walnut (Juglans nigra) Extracts Inhibit Proinflammatory Cytokine Production (Front Pharmacol 2019)","quote":"Native Americans traditionally valued kernels of black walnut … and utilized leaves for medical purposes to treat diarrhea, bilious, and cramp colic … We demonstrated cytokine suppressive properties of black walnut extracts using the human promonocytic cell line U-937","accessed":"2026-08-27"},{"id":"hsa_pr","url":"https://file.go.gov.sg/hsa-chp-prohibited-restricted-ing-guidelines.pdf","label":"HSA — Guidelines on prohibited and restricted ingredients in health supplements and traditional medicines (Oct 2025), Annex A/B","quote":"This list is not exhaustive. Dealers should continue to: Conduct thorough safety assessments of their products","accessed":"2026-08-27"},{"id":"iherb_sg","url":"https://sg.iherb.com/c/black-walnut","label":"iHerb Singapore — category listing, default order","quote":"Nature's Answer · Swanson Vitamins · NOW Foods · Nature's Way · Kroeger Herb Co","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:12.75901+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}