{"ok":true,"entry":{"slug":"bisoprolol","kind":"medication","name":"bisoprolol","aliases":["Concor","Cardicor"],"brands_sg":["Concor","Bisohexal","Bisocor","Blokbis","Bisoccord"],"class":"beta blocker","tags":["heart-bp"],"use_for":"high blood pressure, angina, and stable heart failure","use_after":"once a day, usually in the morning (nhs)","use_duration":null,"take_with":"with or without food · nhs: swallowed whole, not chewed","pros":["sg label: once-daily dosing across its licensed uses","2.5, 5 and 10 mg strengths registered in sg","healthhub: taken with or without food"],"cons":["tiredness, cold hands and feet, a slower heartbeat","sg label: contraindicated in severe bronchial asthma","sg label: stopping abruptly can worsen the condition"],"dose_note":"sg concor label (sin01039p): for hypertension and angina 'the dosage is 5 mg bisoprolol once daily. If necessary, the dose may be increased to 10 mg bisoprolol once daily'; in chronic heart failure, after weekly steps up from 1.25 mg, 'The maximum recommended dose is 10 mg once daily'; in severe renal insufficiency or severe liver disorder 'it is recommended that a daily dose of 10 mg bisoprolol is not exceeded' — as directed on the label or by your doctor","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["asthma or other breathing problems — healthhub: this medication may worsen or cause an asthma attack; severe bronchial asthma is an sg label contraindication","diabetes or pre-diabetes — healthhub: it may hide low-blood-sugar signs such as fast heartbeat or tremors; nhs also flags fasting as not recommended","a slow heart rate, second- or third-degree av block without a pacemaker, sick sinus syndrome, cardiogenic shock or untreated phaeochromocytoma — all sg label contraindications","pregnant or breastfeeding — nhs: extra checks may be offered in pregnancy; it may cause side effects in a breastfed baby"],"clashes":[{"src":["nhs_bisoprolol_med"],"note":"nhs lists heart medicines such as flecainide among those that may not mix well with bisoprolol","with":"heart-rhythm medicines such as flecainide"},{"src":["nhs_bisoprolol_med"],"note":"nhs lists blood pressure medicines such as clonidine among those that may not mix well","with":"other blood pressure medicines such as clonidine"},{"src":["nhs_bisoprolol_med"],"note":"nhs lists painkillers such as ibuprofen among medicines that may not mix well with bisoprolol","with":"painkillers such as ibuprofen (nsaids)"},{"src":["nhs_bisoprolol_med"],"note":"nhs lists medicines used for eye conditions such as glaucoma among those that may not mix well","with":"eye drops for glaucoma"},{"src":["nhs_bisoprolol_med"],"note":"nhs lists medicines to clear a blocked nose among those that may not mix well with bisoprolol","with":"decongestants (medicines for a blocked nose)"},{"src":["nhs_bisoprolol_food"],"food":true,"note":"nhs: drinking alcohol while taking bisoprolol may increase the risk of low blood pressure","with":"alcohol"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/api/action/datastore_search?resource_id=d_767279312753558cbf19d48344577084&limit=6000","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg dataset d_767279312753558cbf19d48344577084), Forensicclassification column; all 5,511 rows pulled once via the datastore_search API and filtered locally, 27 Aug 2026","quote":"CONCOR 5 TABLET 5 mg SIN01039P | Prescription Only; CONCOR TABLET 2.5 mg SIN11349P; BISOHEXAL 5 mg SIN12568P; BISOCOR 5MG SIN15755P; BLOKBIS 5MG SIN15803P; BISOCCORD 5 SIN15852P — all 24 bisoprolol rows 'Prescription Only'; no CARDICOR row.","accessed":"2026-08-27"},{"id":"ndf_concor","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin01039p/","label":"MOH National Drug Formulary (Singapore) — CONCOR 5 TABLET 5 MG [SIN01039P], bisoprolol fumarate, Merck Pte. Ltd. — product info and forensic classification","quote":"BISOPROLOL FUMARATE - 5 MG … TABLET, FILM COATED … Forensic Classification: PRESCRIPTION ONLY MEDICINES … Anatomical Therapeutic Chemical (ATC) code C07AB07 … Prescription-only Medicines with Exemptions for Supply without Prescription: NA","accessed":"2026-08-27"},{"id":"ndf_concor_ind","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin01039p/","label":"MOH National Drug Formulary (Singapore) — CONCOR 5 [SIN01039P], therapeutic indications","quote":"Treatment of hypertension as well as treatment of coronary heart disease (angina pectoris). Treatment of stable chronic heart failure with reduced systolic left ventricular function in addition to ACE inhibitors, and diuretics, and optionally cardiac glycosides","accessed":"2026-08-27"},{"id":"ndf_concor_dose","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin01039p/","label":"MOH National Drug Formulary (Singapore) — CONCOR 5 [SIN01039P], posology: doses, maximum and stopping","quote":"For both indications the dosage is 5 mg bisoprolol once daily. If necessary, the dose may be increased to 10 mg bisoprolol once daily … The maximum recommended dose is 10 mg once daily … Do not stop treatment abruptly","accessed":"2026-08-27"},{"id":"ndf_concor_ci","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin01039p/","label":"MOH National Drug Formulary (Singapore) — CONCOR 5 [SIN01039P], contraindications","quote":"Bisoprolol is contraindicated in patients with: acute heart failure … cardiogenic shock … AV block of second or third degree (without a pacemaker) … sick sinus syndrome … symptomatic bradycardia … severe bronchial asthma … untreated phaeochromocytoma … metabolic acidosis","accessed":"2026-08-27"},{"id":"healthhub_bisoprolol","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/bisoprolol","label":"HealthHub (MOH Singapore) — Bisoprolol, Medication Information Leaflet, last reviewed 21 May 2026","quote":"Bisoprolol belongs to a group of medications known as beta-blockers … You may take this medication with or without food … You have asthma or other breathing problems – this medication may worsen or cause an asthma attack","accessed":"2026-08-27"},{"id":"nhs_bisoprolol","url":"https://www.nhs.uk/medicines/bisoprolol/","label":"NHS medicines A–Z — Bisoprolol (page last reviewed 8 January 2026)","quote":"Bisoprolol is a type of medicine called a beta blocker … Most people take it once a day … at the same time each day, usually in the morning … swallow the tablets whole … do not chew the tablets","accessed":"2026-08-27"},{"id":"nhs_bisoprolol_med","url":"https://www.nhs.uk/medicines/bisoprolol/","label":"NHS medicines A–Z — Bisoprolol, taking it with other medicines, food and drink","quote":"heart medicines, such as flecainide … blood pressure medicines, such as clonidine … medicines used for eye conditions such as glaucoma … painkillers, such as ibuprofen … medicines to clear a blocked nose","accessed":"2026-08-27"},{"id":"nhs_bisoprolol_food","url":"https://www.nhs.uk/medicines/bisoprolol/","label":"NHS medicines A–Z — Bisoprolol, food, drink and alcohol","quote":"You can eat as normal while taking bisoprolol. Drinking alcohol while you're taking bisoprolol may increase the risk of low blood pressure.","accessed":"2026-08-29"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:12.75901+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}