{"ok":true,"entry":{"slug":"betamethasone","kind":"medication","name":"betamethasone","aliases":["Betnovate","Diprosone"],"brands_sg":["Betnovate","Diprosone","Dermasone","Uniflex","Temprosone"],"class":"potent topical corticosteroid","tags":["skin"],"use_for":"eczema, contact dermatitis and psoriasis (nhs)","use_after":"sg label: two or three times daily until it improves","use_duration":null,"take_with":"nhs: about 30 minutes apart from other skin products","pros":["sg label: eczema, psoriasis, insect bites, prickly heat","nhs: safe to use on the skin during pregnancy","sg label: once a day may hold the improvement"],"cons":["nhs: long use can thin skin or cause stretch marks","sg label: not for rosacea, acne or perioral dermatitis","sg label: contraindicated under one year of age"],"dose_note":"the singapore betnovate cream 0.1% label reads ‘a small quantity should be applied to the affected area two or three times daily until improvement occurs. It may then be possible to maintain improvement by applying once a day, or even less often’. the hsa exemption that lets a single-agent topical betamethasone ‘not exceeding 0.1%’ be supplied without a prescription is stricter, and states the ceiling as ‘maximum daily dose: apply to the affected areas twice daily’, ‘maximum supply: 15g for cream/ointment/gel, 30ml for topical solution’, ‘minimum age: 18 years’. nhs adds a duration ceiling: ‘do not use the skin cream, ointment or lotion for more than 4 weeks without talking to your doctor’. as directed on the label or by your doctor.","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["rosacea, acne or perioral dermatitis — sg label: not for those","skin infection or impetigo — nhs says check before using it","under 1 year — sg label: contraindicated in that age group","large areas or long courses — nhs: adrenal and eyesight risks"],"clashes":[{"src":["nhs_bet_mix"],"note":"nhs: about 30 minutes between betamethasone and any other skin treatment","with":"moisturisers and other skin treatments"},{"src":["nhs_bet_mix"],"note":"nhs lists medicines used to treat fungal infections among those to tell a pharmacist or doctor about","with":"itraconazole and other antifungal medicines"},{"src":["nhs_bet_mix"],"note":"nhs lists these among medicines to tell a pharmacist or doctor about before using betamethasone","with":"ritonavir or cobicistat (hiv medicines)"},{"src":["nhs_bet_mix","nhs_bet_se"],"note":"nhs lists other steroid-containing medicines among those to mention; adrenal problems are a rare serious effect","with":"other steroid medicines — creams, inhalers, tablets, drops"},{"src":["ndf_bet_occl","nhs_bet_dress"],"note":"sg label uses occlusion deliberately for resistant plaques; nhs: at least 10 minutes before a dressing, and no dressings on children","with":"occlusion under polythene film or a dressing"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached in full and filtered locally)","quote":"All 54 registered betamethasone rows read 'Prescription Only' — 26 single-ingredient (SIN08247P BETNOVATE CREAM, SIN04025P DIPROSONE, SIN08791P DERMASONE, SIN03849P UNIFLEX, SIN08516P TEMPROSONE) and 28 combinations (FUCICORT, GENTRISONE, DAIVOBET, BEPROSALIC)","accessed":"2026-08-27"},{"id":"nhs_bet_about","url":"https://www.nhs.uk/medicines/betamethasone-skin/","label":"NHS Medicines A-Z — About betamethasone for skin","quote":"Betamethasone skin treatments are used to treat itching, swollen and irritated skin. They can help with conditions such as eczema, contact dermatitis and psoriasis … stronger than some other skin treatments such as hydrocortisone.","accessed":"2026-08-27"},{"id":"nhs_bet_dose","url":"https://www.nhs.uk/medicines/betamethasone-skin/","label":"NHS Medicines A-Z — Betamethasone cream and ointment: how much and how long","quote":"You'll usually use betamethasone skin cream or ointment once or twice a day … Do not use the skin cream, ointment or lotion for more than 4 weeks without talking to your doctor","accessed":"2026-08-27"},{"id":"nhs_bet_dress","url":"https://www.nhs.uk/medicines/betamethasone-skin/","label":"NHS Medicines A-Z — Betamethasone for skin: dressings and bandages","quote":"If you need to use a dressing, like a bandage or plaster, wait at least 10 minutes after putting betamethasone on … If you're treating a child, do not cover the cream or ointment with dressings or bandages.","accessed":"2026-08-27"},{"id":"nhs_bet_who","url":"https://www.nhs.uk/medicines/betamethasone-skin/","label":"NHS Medicines A-Z — Who can use betamethasone for skin","quote":"tell your doctor or a pharmacist if you: have ever had an allergic reaction to betamethasone … have impetigo, acne, rosacea … or a type of psoriasis called plaque psoriasis; have a skin infection; have broken skin, cuts","accessed":"2026-08-27"},{"id":"nhs_bet_se","url":"https://www.nhs.uk/medicines/betamethasone-skin/","label":"NHS Medicines A-Z — Side effects of betamethasone for skin","quote":"Using betamethasone for a long time can make your skin thinner or cause stretch marks … serious side effects, such as adrenal gland problems, high blood sugar (hyperglycaemia), or problems with your eyesight","accessed":"2026-08-27"},{"id":"nhs_bet_preg","url":"https://www.nhs.uk/medicines/betamethasone-skin/","label":"NHS Medicines A-Z — Betamethasone for skin and pregnancy","quote":"Betamethasone skin treatments are safe to use during pregnancy. Because it's applied to your skin, very little medicine gets into your blood and almost none gets to your baby.","accessed":"2026-08-27"},{"id":"nhs_bet_mix","url":"https://www.nhs.uk/medicines/betamethasone-skin/","label":"NHS Medicines A-Z — Cautions with other medicines: betamethasone for skin","quote":"If you're also using any other skin treatment, make sure you wait about 30 minutes … Tell a pharmacist or doctor if you're taking: medicines used to treat HIV, such as ritonavir or cobicistat … such as itraconazole","accessed":"2026-08-27"},{"id":"ndf_bet_ind","url":"https://www.ndf.gov.sg/about-drugs/product-information/SIN08247P","label":"National Drug Formulary (SG, MOH) — BETNOVATE CREAM 0.1% w/w [SIN08247P]: approved indications","quote":"Eczema including atopic, infantile, and discoid eczemas; Prurigo nodularis; Psoriasis (excluding widespread plaque psoriasis); Neurodermatoses including lichen simplex, lichen planus; Seborrhoeic dermatitis … Insect bite reactions; Prickly heat","accessed":"2026-08-27"},{"id":"ndf_bet_dose","url":"https://www.ndf.gov.sg/about-drugs/product-information/SIN08247P","label":"National Drug Formulary (SG, MOH) — BETNOVATE CREAM 0.1% w/w [SIN08247P]: dosage and administration","quote":"A small quantity should be applied to the affected area two or three times daily until improvement occurs. It may then be possible to maintain improvement by applying once a day, or even less often.","accessed":"2026-08-27"},{"id":"ndf_bet_occl","url":"https://www.ndf.gov.sg/about-drugs/product-information/SIN08247P","label":"National Drug Formulary (SG, MOH) — BETNOVATE CREAM 0.1% w/w [SIN08247P]: occlusion in resistant lesions","quote":"In the more resistant lesions, such as the thickened plaques of psoriasis on elbows and knees, the effect of BETNOVATE can be enhanced, if necessary, by occluding the treatment area with polythene film.","accessed":"2026-08-27"},{"id":"ndf_bet_exempt","url":"https://www.ndf.gov.sg/about-drugs/product-information/SIN08247P","label":"National Drug Formulary (SG, MOH) — BETNOVATE CREAM [SIN08247P]: prescription-only medicine with exemption for supply without prescription","quote":"As a topical preparation (as valerate or dipropionate salt) as a single agent not exceeding 0.1% … Maximum Daily Dose: Apply to the affected areas twice daily. Maximum Supply: 15g for cream/ointment/gel, 30ml for topical solution. Minimum age: 18 years","accessed":"2026-08-27"},{"id":"ndf_bet_contra","url":"https://www.ndf.gov.sg/about-drugs/product-information/SIN08247P","label":"National Drug Formulary (SG, MOH) — BETNOVATE CREAM 0.1% w/w [SIN08247P]: contraindications","quote":"The following conditions should not be treated with BETNOVATE: Rosacea, Acne vulgaris, Perioral dermatitis, Perianal and genital pruritus … BETNOVATE is contraindicated in dermatoses in infants under one year of age.","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:12.75901+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}