{"ok":true,"entry":{"slug":"betahistine","kind":"medication","name":"betahistine","aliases":["Serc","Betaserc"],"brands_sg":["Betaserc","Merislon","GP-Betahistine"],"class":"histamine analogue","tags":["other"],"use_for":"vertigo, tinnitus and hearing loss in ménière's disease","use_after":"healthhub: with or after food · sg label: divided doses","use_duration":null,"take_with":"water — the sg label says the tablet is swallowed with it","pros":["sg label: covers vertigo, hearing loss and tinnitus","healthhub: nausea eases if taken with or after food","sg label: the dose is adapted to the response"],"cons":["hsa: prescription-only in singapore","healthhub: nausea, headache and indigestion","sg label: improvement can take weeks or months"],"dose_note":"the singapore package insert for betaserc 24 tablet 24 mg (SIN12235P), as published on the moh national drug formulary, states \"The dosage for adults is 24–48 mg divided over the day\" and \"Should be swallowed with water\" — 48 mg a day is the top of the adult label range, with no higher step listed. the same insert adds \"The dosage should be individually adapted according to the response\" and that \"Betaserc is not recommended for use in children under the age of 18 years due to insufficient data on safety and efficacy\". the sg register also carries a 6 mg mesylate tablet (merislon) and 16 mg and 24 mg dihydrochloride tablets, so the tablet count behind that 48 mg differs by brand. in singapore the prescriber sets the dose.","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["phaeochromocytoma — an sg label contraindication","peptic ulcer, asthma, heart or liver disease (healthhub)","under 18 — the sg label does not recommend it","pregnancy, planning pregnancy or breastfeeding (healthhub)"],"clashes":[{"src":["nhs_beta_int"],"note":"nhs: used for depression or parkinson's disease; can increase the chance of side effects","with":"mao inhibitors"},{"src":["nhs_beta_int"],"note":"nhs: betahistine and antihistamines affect each other","with":"antihistamines for allergies such as hay fever"},{"src":["nhs_beta_int"],"note":"nhs: there is not enough information to say they are safe with betahistine","with":"herbal remedies and supplements"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg dataset d_767279312753558cbf19d48344577084), Forensicclassification column; 5,511 rows cached at /tmp/hsa_all.json and filtered locally, never re-fetched — 4 betahistine rows","quote":"All 4 registered betahistine products read \"Prescription Only\", ATC N07CA01 — SIN12235P BETASERC 24 TABLET 24 mg, SIN11365P BETASERC TABLETS 16 mg, SIN03047P MERISLON TABLET 6 mg, SIN16812P GP-BETAHISTINE TABLETS 24MG.","accessed":"2026-08-27"},{"id":"ndf_betaserc_ind","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin12235p/","label":"MOH National Drug Formulary — BETASERC 24 TABLET 24 MG [SIN12235P], Therapeutic Indications (SG package insert)","quote":"Ménière's Syndrome as defined by the following core symptoms: Vertigo (with nausea/vomiting); Hearing loss (hardness of hearing); Tinnitus (ringing in the ears). Symptomatic treatment of vestibular vertigo.","accessed":"2026-08-27"},{"id":"ndf_betaserc_dose","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin12235p/","label":"MOH National Drug Formulary — BETASERC 24 TABLET 24 MG [SIN12235P], Posology and method of administration","quote":"The dosage for adults is 24–48 mg divided over the day. Should be swallowed with water. The dosage should be individually adapted according to the response. Improvement can sometimes only be observed after a couple of weeks of treatment.","accessed":"2026-08-27"},{"id":"ndf_betaserc_ci","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin12235p/","label":"MOH National Drug Formulary — BETASERC 24 TABLET 24 MG [SIN12235P], Contraindications and paediatric wording","quote":"Hypersensitivity to the active substance or to any of the excipients. Phaeochromocytoma … Betaserc is not recommended for use in children under the age of 18 years due to insufficient data on safety and efficacy.","accessed":"2026-08-27"},{"id":"ndf_betaserc_class","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin12235p/","label":"MOH National Drug Formulary — BETASERC 24 TABLET 24 MG [SIN12235P], product information block","quote":"Forensic Classification: PRESCRIPTION ONLY MEDICINES · Anatomical Therapeutic Chemical (ATC) code N07CA01 · Prescription-only Medicines with Exemptions for Supply without Prescription: NA","accessed":"2026-08-27"},{"id":"hh_beta_uses","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/betahistine","label":"HealthHub (National Medication Information workgroup / Pharmaceutical Society of Singapore) — Betahistine: what is this medication for","quote":"Betahistine is used to treat vertigo (dizzy spells), tinnitus (ringing in the ear), hearing loss, nausea or vomiting associated with Meniere disease or vertigo due to inner ear problem. There are two types of salt … mesilate and dihydrochloride.","accessed":"2026-08-27"},{"id":"hh_beta_admin","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/betahistine","label":"HealthHub — Betahistine: how should I take or use this medication","quote":"You may take this medication with or after food. Follow the instructions on the medication label and take this medication as prescribed by your doctor.","accessed":"2026-08-27"},{"id":"hh_beta_prec","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/betahistine","label":"HealthHub — Betahistine: what precautions should I take","quote":"You are pregnant, planning to become pregnant, or breastfeeding … Medical conditions such as heart or liver disease, peptic ulcer, pheochromocytoma (tumour on the adrenal gland) or asthma","accessed":"2026-08-27"},{"id":"hh_beta_se","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/betahistine","label":"HealthHub — Betahistine: common side effects","quote":"Nausea — Take with or after food to reduce the symptom. Headache. Stomach discomfort such as indigestion.","accessed":"2026-08-27"},{"id":"nhs_beta_hub","url":"https://www.nhs.uk/medicines/betahistine/","label":"NHS — Betahistine: a medicine to treat Ménière's disease (brand name Serc)","quote":"Betahistine - Brand name: Serc. Find out how betahistine treats symptoms of Ménière's disease and how to take it.","accessed":"2026-08-27"},{"id":"nhs_beta_int","url":"https://www.nhs.uk/medicines/betahistine/taking-betahistine-with-other-medicines-and-herbal-supplements/","label":"NHS — Taking betahistine with other medicines and herbal supplements","quote":"Tell your pharmacist or doctor if you're taking: medicines called MAO inhibitors, used to treat depression or Parkinson's disease; antihistamines for allergies such as hay fever … There's not enough information to say that complementary medicines … are safe","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:12.75901+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}