{"ok":true,"entry":{"slug":"baclofen","kind":"medication","name":"baclofen","aliases":["Lioresal"],"brands_sg":["Lioresal","Colmifen","Apo-Baclofen","PMS-Baclofen"],"class":"muscle relaxant","tags":["other"],"use_for":"nhs: muscle spasms and tightness from nerve conditions","use_after":"nhs: usually 3 times a day · tapered, not stopped abruptly","use_duration":null,"take_with":"healthhub: with or after food · nhs: or a glass of milk","pros":["healthhub: full benefit in about three to four days","nhs: comes as tablets or a liquid you swallow","nhs: most adults and children over 1 month can take it"],"cons":["nhs: drowsiness, dizziness, dry mouth and nausea","healthhub: stopping suddenly can trigger fits or fever","nhs: rare very low mood and suicidal thoughts"],"dose_note":"no singapore package insert was read. the us label for baclofen tablets states \"Start therapy at a low dosage and increase gradually until optimum effect is achieved (usually between 40-80 mg daily) … Thereafter additional increases may be necessary but the total daily dose should not exceed a maximum of 80 mg daily (20 mg q.i.d.)\" — 80 mg a day is the adult label maximum for the tablets, reached over a suggested titration of 5 mg three times a day rising in 5 mg steps every 3 days. every sg-registered baclofen product is a 10 mg tablet. in singapore the prescriber sets the dose.","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["respiratory or kidney disease (healthhub)","stroke, stomach problems or urinary retention (healthhub)","seizures, parkinson's disease or cerebral palsy (healthhub)","psychosis or schizophrenia — healthhub asks that this be declared"],"clashes":[{"src":["hh_bac_avoid","nhs_bac_mix"],"food":true,"note":"healthhub: it can cause excessive sleepiness; nhs agrees on tiredness","with":"alcohol"},{"src":["nhs_bac_mix"],"note":"nhs lists these among medicines that may not mix well","with":"other muscle relaxants such as tizanidine"},{"src":["nhs_bac_mix"],"note":"nhs lists mental-health medicines among those that may not mix well","with":"lithium or amitriptyline"},{"src":["nhs_bac_mix"],"note":"nhs lists these among medicines that may not mix well","with":"diltiazem and other blood pressure medicines"},{"src":["nhs_bac_mix"],"note":"nhs lists morphine, buprenorphine, temazepam and promethazine","with":"opioids, sedatives and sedating antihistamines"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg dataset d_767279312753558cbf19d48344577084), Forensicclassification column; all 5,511 rows cached at /tmp/hsa_all.json and filtered locally (not re-fetched), baclofen rows, 27 Aug 2026","quote":"LIORESAL 10 TABLET 10 mg SIN05330P · COLMIFEN 10 SIN06831P · APO-BACLOFEN SIN09087P · PMS-BACLOFEN SIN10026P — ATC M03BX01, every row 10 mg; all 4 baclofen rows read Forensicclassification \"Prescription Only\"","accessed":"2026-08-27"},{"id":"nhs_bac_about","url":"https://www.nhs.uk/medicines/baclofen/","label":"NHS medicines A–Z — Baclofen: what baclofen is for (reviewed 23 July 2026)","quote":"Baclofen is a muscle relaxant medicine used to ease muscle spasms. It's only available with a prescription … cramps or tightness caused by conditions that affect your nerves and brain (nervous system).","accessed":"2026-08-27"},{"id":"nhs_bac_howto","url":"https://www.nhs.uk/medicines/baclofen/","label":"NHS medicines A–Z — Baclofen: how to take baclofen","quote":"Baclofen usually comes as tablets or a liquid (oral solution) that you swallow. You usually take it 3 times a day … it's best to take it with food or a glass of milk","accessed":"2026-08-27"},{"id":"nhs_bac_stop","url":"https://www.nhs.uk/medicines/baclofen/","label":"NHS medicines A–Z — Baclofen: how to stop taking baclofen","quote":"If you need to stop taking baclofen, do not suddenly stop taking it because it may cause withdrawal symptoms. Your doctor will gradually reduce your dose over several weeks or months.","accessed":"2026-08-27"},{"id":"nhs_bac_side","url":"https://www.nhs.uk/medicines/baclofen/","label":"NHS medicines A–Z — Baclofen: side effects","quote":"Common side effects of baclofen include: headaches; dry mouth; feeling tired or weak; feeling dizzy or faint; feeling sick (nausea) … having a very low mood and having suicidal thoughts","accessed":"2026-08-27"},{"id":"nhs_bac_who","url":"https://www.nhs.uk/medicines/baclofen/","label":"NHS medicines A–Z — Baclofen: who can and cannot take baclofen","quote":"Most adults and children aged 1 month or over can take baclofen.","accessed":"2026-08-27"},{"id":"nhs_bac_mix","url":"https://www.nhs.uk/medicines/baclofen/","label":"NHS medicines A–Z — Baclofen: taking baclofen with other medicines, food and drink","quote":"other muscle relaxants, such as tizanidine; medicines for mental health conditions, such as lithium or amitriptyline; medicines for high blood pressure, such as diltiazem; … promethazine, or sedatives, such as temazepam; opioid painkillers, such as morphine","accessed":"2026-08-27"},{"id":"hh_bac_uses","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/baclofen","label":"HealthHub (Pharmaceutical Society of Singapore / MOH) — Baclofen: what is this medication for","quote":"Baclofen is a muscle relaxant. It is used to improve the symptoms of muscle stiffness and spasms due to injuries to your spinal cord. It also helps to ease your pain and improve your movements.","accessed":"2026-08-27"},{"id":"hh_bac_howto","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/baclofen","label":"HealthHub — Baclofen: how should I take or use this medication","quote":"Baclofen may be taken with or after food … it may take around three to four days before you can feel its full benefits","accessed":"2026-08-27"},{"id":"hh_bac_stop","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/baclofen","label":"HealthHub — Baclofen: stopping this medication","quote":"You may experience unpleasant effects such as muscle stiffness, cramps, fast heart rate, fever, confusion or seizures (fits) if you stop taking baclofen suddenly.","accessed":"2026-08-27"},{"id":"hh_bac_prec","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/baclofen","label":"HealthHub — Baclofen: what precautions should I take","quote":"You have or have ever had: Other drug allergies; Respiratory or kidney disease; Medical conditions such as: Stroke; Stomach problems; Seizures (fits), Parkinson's disease, or Cerebral Palsy; Urinary retention; Mental health conditions such as psychosis or Schizophrenia","accessed":"2026-08-27"},{"id":"hh_bac_avoid","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/baclofen","label":"HealthHub — Baclofen: what food or medication should I avoid","quote":"Avoid drinking alcohol while taking Baclofen as it can cause excessive sleepiness.","accessed":"2026-08-27"},{"id":"fda_bac_dose","url":"https://api.fda.gov/drug/label.json?search=openfda.generic_name:%22baclofen%22&limit=5","label":"US label for baclofen tablets USP (REMEDYREPACK, effective 2026-01-21) via openFDA drug/label.json, Dosage and Administration","quote":"Start therapy at a low dosage and increase gradually until optimum effect is achieved (usually between 40-80 mg daily) … the total daily dose should not exceed a maximum of 80 mg daily (20 mg q.i.d.).","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:12.75901+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}