{"ok":true,"entry":{"slug":"astragalus","kind":"supplement","name":"astragalus","aliases":["Astragalus membranaceus","huang qi","bei qi"],"brands_sg":["NOW Foods","Nutricost","Swanson Vitamins","Nature's Way","Vitamatic"],"class":"botanical","tags":["immune","energy"],"use_for":"promoted for immunity and fatigue — evidence not sufficient","use_after":null,"use_duration":null,"take_with":null,"pros":["root used for centuries in traditional chinese medicine","a 2023 review of 19 studies saw immune-marker changes","up to 60 g/day for 4 months: no adverse effects seen"],"cons":["nccih: not enough reliable evidence for any condition","the immune studies were small and ran very differently","no thorough safety evaluation has been done"],"dose_note":"nccih states there is not sufficient reliable scientific evidence to know whether astragalus is useful for any health condition; it is promoted for upper respiratory infections, allergic rhinitis, asthma, chronic fatigue syndrome and immune response, and topically for wound healing, none of which is established; a 2023 review of 19 studies in 1,094 participants found astragalus enhanced immune responses and reduced proinflammatory cytokines, but the studies were small and differed widely in how they were done; on safety nccih says astragalus may be safe when used orally — taking up to 60 grams per day for as long as 4 months does not seem to cause adverse effects — while adding that a thorough safety evaluation has not been done, and that there is not enough reliable information about applying it to the skin; no rda, ul, fda daily value or hsa singapore daily limit exists for astragalus","dosage":{"ul":null,"unit":null,"fda_dv":null,"rda_ai":null,"ul_status":"none_established","population":"general adult","hsa_max_daily":null},"ul_status":"none_established","sg_class":null,"cautions":["autoimmune disease — nccih says astragalus might worsen symptoms","on medicines that suppress the immune system — nccih flags an interaction","pregnant or breastfeeding — little is known; animal data suggest fetal toxicity","not listed in hsa's prohibited or restricted annexes — that is not a safety finding"],"clashes":[{"src":["nccih_astragalus_safety"],"note":"nccih says astragalus may interact with medications that suppress the immune system","with":"immunosuppressant medicines"}],"sources":[{"id":"nccih_astragalus","url":"https://www.nccih.nih.gov/health/astragalus","label":"NIH NCCIH — Astragalus, last updated May 2025","quote":"There is not sufficient reliable scientific evidence to know whether astragalus is useful for any health condition.","accessed":"2026-08-27"},{"id":"nccih_astragalus_uses","url":"https://www.nccih.nih.gov/health/astragalus","label":"NIH NCCIH — Astragalus, Background section","quote":"astragalus has been promoted as a dietary supplement for many conditions, including upper respiratory infections, allergic rhinitis (hay fever), asthma, chronic fatigue syndrome, chronic kidney disease, and diabetes. It's also promoted to improve the response of the immune system.","accessed":"2026-08-27"},{"id":"nccih_astragalus_immune","url":"https://www.nccih.nih.gov/health/astragalus","label":"NIH NCCIH — Astragalus, What Have We Learned (2023 immune review)","quote":"A 2023 review of 19 studies (involving 1,094 participants) found that astragalus enhanced immune responses and reduced levels of proinflammatory cytokines … The studies were small, and there were many differences in how the studies were done, however.","accessed":"2026-08-27"},{"id":"nccih_astragalus_safety","url":"https://www.nccih.nih.gov/health/astragalus","label":"NIH NCCIH — Astragalus, What Do We Know About Safety","quote":"Because astragalus might worsen symptoms of autoimmune diseases, people with autoimmune diseases should avoid using astragalus. Also, astragalus may interact with medications that suppress the immune system","accessed":"2026-08-27"},{"id":"nccih_astragalus_dose","url":"https://www.nccih.nih.gov/health/astragalus","label":"NIH NCCIH — Astragalus, What Do We Know About Safety (oral use)","quote":"Astragalus may be safe when used orally. (Taking up to 60 grams per day for as long as 4 months does not seem to cause adverse effects.) However, a thorough safety evaluation has not been done.","accessed":"2026-08-27"},{"id":"nccih_astragalus_pregnancy","url":"https://www.nccih.nih.gov/health/astragalus","label":"NIH NCCIH — Astragalus, What Do We Know About Safety (pregnancy)","quote":"Little is known about whether it's safe to use astragalus during pregnancy or while breastfeeding. Some research in animals suggests that during pregnancy, astragalus can be toxic to the fetus.","accessed":"2026-08-27"},{"id":"hsa_prohibited","url":"https://file.go.gov.sg/hsa-chp-prohibited-restricted-ing-guidelines.pdf","label":"HSA Singapore — Guidelines on Prohibited and Restricted Ingredients in Health Supplements and Traditional Medicines, GL-CHPB-1-012 Rev. No. 001 (October 2025), Annex A (118 rows) and Annex B (4 rows) — Astragalus not listed in either","quote":"The objective of this guideline is to highlight the substances of concern when used in HS and TM and is not meant to be an exhaustive list.","accessed":"2026-08-27"},{"id":"hsa_hs_guidelines","url":"https://file.go.gov.sg/hsa-hs-guidelines.pdf","label":"HSA Singapore — Health Supplements Guidelines GL-CHPB-3-001 Rev. No. 020 (January 2026), clause 4.8 with Tables 4–5 (vitamins and minerals only — no botanical rows)","quote":"4.8 HS for use by the general adult population should not contain vitamins and minerals exceeding the stipulated limits stated in Tables 4 and 5.","accessed":"2026-08-27"},{"id":"iherb_sg","url":"https://sg.iherb.com/c/astragalus","label":"iHerb Singapore — Astragalus category page, default listing order","quote":"1 - 43 of 43 results … NOW Foods, Astragalus Extract, 500 mg … Nutricost, Astragalus Root, 550 mg … Swanson Vitamins, Full Spectrum® Astragalus Root, 470 mg … Nature's Way, Astragalus Root … Vitamatic, Astragalus, 5,000 mg","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:10.48466+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}