{"ok":true,"entry":{"slug":"ambroxol","kind":"medication","name":"ambroxol","aliases":["Mucosolvan","Mucosolvan Junior","ambroxol hydrochloride"],"brands_sg":["Mucosolvan","Strepsils Cough for Chesty Cough","Shinoxol","Polibroxol","Amxol"],"class":"mucolytic","tags":["cold-flu"],"use_for":"chesty cough — thins mucus or phlegm in the air passages","use_after":"1 tablet three times daily per the mucosolvan 30 mg label","use_duration":null,"take_with":"after food per healthhub · capsules with or without food","pros":["all four mucosolvan products are general sale list","cochrane: one trial favoured mucolytics over placebo","healthhub: tablet, prolonged-release capsule or syrup"],"cons":["4 of 8 sg registrations are prescription only","cochrane: no good evidence for or against otc cough","nausea, vomiting and abdominal pain are common"],"dose_note":"the singapore mucosolvan tablet 30 mg label [SIN02696P] reads 'the recommended dose for adults is 1 tablet 3 times daily. For better effect, you may administer 2 tablets 2 times daily' — the largest amount the label states is 2 tablets twice daily, 120 mg a day, and it carries no explicit 'do not exceed' line; the same label says 'Mucosolvan is not recommended for children under 2 years of age without medical advice' and 'you should contact a doctor if your symptoms worsen or do not improve after 4 – 5 days'; as directed on the label or by your doctor or pharmacist","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["gastric ulcers, liver or kidney problems, copd or severe uncontrolled asthma — healthhub says say so first","cough with thick yellow or green phlegm or blood, fever above 38.6 °C, night sweats or weight loss — healthhub says say so first","pregnant, planning to be, or breastfeeding — healthhub says say so first","under 2 — the mucosolvan label says not recommended without medical advice"],"clashes":[{"src":["healthhub_ambrox_precautions"],"note":"healthhub asks that you tell your healthcare professional what else you are taking; no specific interaction is named","with":"other medicines, supplements, traditional or herbal remedies"},{"src":["ndf_mucosolvan"],"note":"the mucosolvan sg patient leaflet published on ndf lists no interaction section — untested, not shown safe","with":"nothing else documented on the sg label"}],"sources":[{"id":"healthhub_ambrox","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/ambroxol","label":"HealthHub (MOH Singapore) — Ambroxol, uses / administration / side effects (article last reviewed 17 Mar 2026)","quote":"Ambroxol is a type of mucolytic that works by thinning and loosening mucus or phlegm in the airways … It may come in tablet, prolonged-release capsule or syrup form … You should take Ambroxol after food","accessed":"2026-08-27"},{"id":"healthhub_ambrox_precautions","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/ambroxol","label":"HealthHub (MOH Singapore) — Ambroxol, precautions and side-effect sections (article last reviewed 17 Mar 2026)","quote":"gastric ulcers, liver or kidney problems and lung conditions e.g. Chronic Obstructive Lung Disease (COPD) or severe uncontrolled asthma … Common side effects may include nausea, vomiting and abdominal pain","accessed":"2026-08-27"},{"id":"ndf_mucosolvan","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin02696p/","label":"MOH National Drug Formulary — MUCOSOLVAN TABLET 30 MG [SIN02696P], Dosing section of the SG patient leaflet","quote":"The recommended dose for adults is 1 tablet 3 times daily. For better effect, you may administer 2 tablets 2 times daily … Mucosolvan is not recommended for children under 2 years of age without medical advice","accessed":"2026-08-27"},{"id":"ndf_mucosolvan_class","url":"https://www.ndf.gov.sg/about-drugs/product-information/sin02696p/","label":"MOH National Drug Formulary — MUCOSOLVAN TABLET 30 MG [SIN02696P], forensic classification and exemption fields","quote":"Forensic Classification GENERAL SALE LIST … Prescription-only Medicines with Exemptions for Supply without Prescription: As an oral solid preparation containing not more than 30mg.","accessed":"2026-08-27"},{"id":"hsa_register_ambrox","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA register of therapeutic products (data.gov.sg d_767279312753558cbf19d48344577084) — 8 ambroxol rows, filtered locally 27 Aug 26","quote":"MUCOSOLVAN TABLET 30 mg … General Sale List … Mucosolvan 24 Hours Capsule 75mg … STREPSILS COUGH FOR CHESTY COUGH LOZENGE … SHINOXOL TABLETS 30 mg … Prescription Only … POLIBROXOL … AMXOL … AXOL LIQUID","accessed":"2026-08-27"},{"id":"cochrane2014","url":"https://europepmc.org/article/PMC/PMC7061814","label":"Cochrane Database of Systematic Reviews — OTC medications for acute cough in children and adults in community settings (Smith, Schroeder, Fahey 2014; PMC7061814)","quote":"The results of one trial favoured active treatment with mucolytics over placebo … There is no good evidence for or against the effectiveness of OTC medicines in acute cough","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:10.48466+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}