{"ok":true,"entry":{"slug":"alfuzosin","kind":"medication","name":"alfuzosin","aliases":["Xatral"],"brands_sg":["Xatral XL","Ranfuzosin","Apo-Alfuzosin"],"class":"alpha-1 blocker","tags":["other"],"use_for":"prescribed for an enlarged prostate (bph)","use_after":"healthhub: after food, a new dose started at bedtime","use_duration":null,"take_with":"food · fda label: with the same meal each day","pros":["healthhub: relaxes prostate and bladder-exit muscles","fda label: one 10 mg tablet once daily","healthhub: first-dose dizziness usually settles"],"cons":["healthhub: dizziness, light-headedness or fainting","healthhub: drowsiness can affect driving","fda: floppy iris during cataract surgery"],"dose_note":"the us fda label for uroxatral (alfuzosin hcl extended-release) states 'The recommended dosage is one 10 mg UROXATRAL (alfuzosin HCl) extended-release tablet once daily' — 10 mg once daily is the adult label maximum, and the same label says uroxatral 'is not indicated for use in the pediatric population'. all three alfuzosin products on the sg register are 10 mg prolonged-release tablets. in singapore the prescriber sets the dose.","dosage":null,"ul_status":null,"sg_class":"prescription-only","cautions":["heart problems, or dizziness or fainting on standing (healthhub)","cataract surgery planned — healthhub: tell the eye specialist","moderate or severe liver impairment — fda: contraindicated","severe kidney impairment — fda: use with caution"],"clashes":[{"src":["hh_alfu_precautions","fda_alfu_di"],"note":"healthhub and fda: both lower blood pressure; dizziness or light-headedness on standing","with":"pde-5 inhibitors (sildenafil, tadalafil, vardenafil)"},{"src":["fda_alfu_ci"],"note":"fda: contraindicated — these potent cyp3a4 inhibitors raise alfuzosin blood levels","with":"ketoconazole, itraconazole, ritonavir"},{"src":["fda_alfu_di"],"note":"fda: should not be used in combination with other alpha adrenergic antagonists","with":"other alpha blockers"},{"src":["fda_alfu_di"],"note":"fda: increased risk of hypotension, postural hypotension and syncope","with":"blood pressure medicines and nitrates"},{"src":["hh_alfu_food"],"food":true,"note":"healthhub: may increase the risk of dizziness, light-headedness or drowsiness","with":"alcohol"}],"sources":[{"id":"hsa_register","url":"https://data.gov.sg/datasets/d_767279312753558cbf19d48344577084/view","label":"HSA — Listing of Registered Therapeutic Products (data.gov.sg open dataset, 5,511 rows, cached locally at /tmp/hsa_all.json and filtered locally)","quote":"All 3 registered alfuzosin products carry Forensicclassification 'Prescription Only' — SIN11579P XATRAL XL TABLET 10 mg · SIN13984P RANFUZOSIN MODIFIED RELEASE TABLETS 10MG · SIN15512P APO-ALFUZOSIN PROLONGED RELEASE TABLET 10mg (ATC G04CA01)","accessed":"2026-08-27"},{"id":"hh_alfu_uses","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/alfuzosin","label":"HealthHub (Pharmaceutical Society of Singapore) — Alfuzosin: what is this medication for","quote":"Alfuzosin belongs to a group of medications known as alpha-1 blockers. It is used to treat benign prostatic hyperplasia … The medication works by relaxing the muscles of the prostate gland and bladder exit","accessed":"2026-08-27"},{"id":"hh_alfu_admin","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/alfuzosin","label":"HealthHub — Alfuzosin: how should I take or use this medication","quote":"This medication should be taken after food … Do not crush or chew the tablet … The first tablet of a new dose should be taken at bedtime, and subsequently at the same time each day.","accessed":"2026-08-27"},{"id":"hh_alfu_precautions","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/alfuzosin","label":"HealthHub — Alfuzosin: what precautions should I take","quote":"You have heart problems … You ever feel dizzy or faint when you stand up … You are undergoing cataract eye surgery … You are taking medications belonging to PDE-5 Inhibitors class such as Sildenafil, Tadalafil","accessed":"2026-08-27"},{"id":"hh_alfu_se","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/alfuzosin","label":"HealthHub — Alfuzosin: common side effects","quote":"Dizziness, light-headedness or fainting … These side effects usually go away and should not return once you have become used to taking your medication. Drowsiness — May affect your ability to drive","accessed":"2026-08-27"},{"id":"hh_alfu_food","url":"https://www.healthhub.sg/medication-devices-and-treatment/medications/alfuzosin","label":"HealthHub — Alfuzosin: what food or medication should I avoid","quote":"Avoid drinking alcohol as it may increase the risk of dizziness, light-headedness or drowsiness.","accessed":"2026-08-27"},{"id":"fda_alfu_dose","url":"https://api.fda.gov/drug/label.json?search=openfda.brand_name:%22UROXATRAL%22&limit=1","label":"US FDA label for UROXATRAL (alfuzosin HCl extended-release tablets), sections 1–2, via openFDA drug/label.json (effective 2024-12-05)","quote":"The recommended dosage is one 10 mg UROXATRAL (alfuzosin HCl) extended-release tablet once daily … Uroxatral should be taken with food and with the same meal each day … not indicated for use in the pediatric population","accessed":"2026-08-27"},{"id":"fda_alfu_ci","url":"https://api.fda.gov/drug/label.json?search=openfda.brand_name:%22UROXATRAL%22&limit=1","label":"US FDA label for UROXATRAL, section 4 Contraindications, via openFDA","quote":"UROXATRAL is contraindicated for use: in patients with moderate or severe hepatic impairment (Childs-Pugh categories B and C) … with potent CYP3A4 inhibitors such as ketoconazole, itraconazole, and ritonavir","accessed":"2026-08-27"},{"id":"fda_alfu_warn","url":"https://api.fda.gov/drug/label.json?search=openfda.brand_name:%22UROXATRAL%22&limit=1","label":"US FDA label for UROXATRAL, section 5 Warnings and Precautions, via openFDA","quote":"Postural hypotension/syncope … Use with caution in patients with severe renal impairment … Intraoperative Floppy Iris Syndrome (IFIS) during cataract surgery may require modifications to the surgical technique","accessed":"2026-08-27"},{"id":"fda_alfu_di","url":"https://api.fda.gov/drug/label.json?search=openfda.brand_name:%22UROXATRAL%22&limit=1","label":"US FDA label for UROXATRAL, section 7 Drug Interactions, via openFDA","quote":"Concomitant use of PDE5 inhibitors with alpha adrenergic antagonists, including UROXATRAL, can potentially cause symptomatic hypotension … UROXATRAL should not be used in combination with other alpha adrenergic antagonists","accessed":"2026-08-27"}],"brand_certs":null,"updated_at":"2026-08-29T16:16:10.48466+08:00"},"disclaimer":"kozen-x is not a medical device and does not give medical advice. it lists what published sources have written down. absence of a record is not the same as safe."}